Pruritic urticarial papules and plaques of Pregnancy Contact dermatitis Drug eruption Urticaria Erythema multiforme Varicella Other autoimmune blistering diseases 32.6 Associated Conditions PG has been associated with patients diagnosed with…
Fig. 23.1 Clinical features of pemphigus foliaceus/fogo selvagem. (a) Localized (forme fruste), erosion(s) and/or crusted lesion(s) on photo-exposed/seborrheic areas. (b) Bullous invasive (generalized variant), disseminated superficial vesicles/blisters. No mucosal involvement….
EB type or subtype United States Italy Australia Norway Japan Croatia Others EBS 4.6 10.5 42.0 2.9–4.0 1.5 28.6a EBS-loc 3.1 14.5 0.4 EBS-K 1.4 1.1 EBS-loc/K 5.5 JEB 0.4 …
Fig. 21.1 Relative incidence of pemphigus vulgaris in different populations. The percentage of pemphigus vulgaris in relation to all pemphigus cases is shown 21.2.1 Incidence The incidence of pemphigus considerably…
Fig. 10.1 Distribution and domain structure of kindlin-1. (a) Kindlin-1 (green, arrows) is demonstrated in keratinocytes at focal adhesions and in the epidermis at the dermal-epidermal junction by indirect immunofluorescence…
© Springer-Verlag Berlin Heidelberg 2015Dédée F. Murrell (ed.)Blistering Diseases10.1007/978-3-662-45698-9_20 20. Prenatal Diagnosis of Epidermolysis Bullosa: Current Aspects and Perspectives Araksya Izmiryan1 and Alain Hovnanian2 (1) INSERM UMR 1163, Laboratory of Genetic Skin Diseases, Hôpital Necker Enfants…
Mutation (cDNA level)a Mutation (protein level) Other designations used in original publications Exon Genotype EBS-MD 954_956dupGCT L319dup 956ins3, 1008ins3, 1287ins3 9 c.het. (Q1408X) 968G>A R323Q 9 c.het. (E1614X) 1530_1531ins36 A510_I511ins12…
Fig. 9.1 Molecular organisation of laminin 332 in the dermal–epidermal junction. (a) Structure of human laminin 332 (Modified from Rousselle and Beck [85]). Laminin 332 is composed of three subunits:…
Fig. 2.1 Schematic structure of the skin and immune cells. Various immune cells reside in the two major compartments of the skin, the dermis and the epidermis. Epidermal dendritic cells…
Fig. 4.1 (a) By transmission electron microscopy numerous desmosome cell-cell junctions are present between adjacent keratinocytes; (b) higher magnification of boxed area in (a) shows intracellular and extracellular desmosome morphology;…
