Angiogenesis and Pathogenesis of Port Wine Stain and Infantile Hemangiomas
Fig. 8.1 (a) Adolescent male with PWS; (b) same male with PWS at 42 years of age. Note vascular nodules and soft tissue hypertrophy in (b) (Reprinted with permission from…
Dermatology
Chemoprevention and Angiogenesis
Fig. 7.1 Cancer transformation is a multi-stage process and chemopreventive strategies should aim to target the exposure (1), and/or initial cancer formation (2) or (3) cancer promotion This ROS induced…
Angiogenesis and Nonmelanoma Skin Cancer
(1) Department of Dermatology, Cleveland Clinic Foundation, Cleveland, OH, USA (2) Department of Dermatology, Division of Dermatologic Surgery, Wilmot Cancer Center, University of Rochester, 400 Red Creek Drive, Suite 200,…
Angiogenesis: General Concepts
Fig. 1.1 Morphological differences between capillary beds of various tissues. Confocal micrographs of blood vessels, shown in green, found in the retina, inner and outer choroid, skin, brain, heart, liver…
Infantile Hemangioma: New Insights on Pathogenesis and Beta Blockers Mechanisms of Action
© Springer-Verlag London Ltd. 2017Jack L. Arbiser (ed.)Angiogenesis-Based Dermatology10.1007/978-1-4471-7314-4_2 2. Infantile Hemangioma: New Insights on Pathogenesis and Beta Blockers Mechanisms of Action Shoshana Greenberger1 (1) The Department of Dermatology and Sheba Cancer Research Center, Sheba…
The Importance of Stratum Corneum Lipid Organization for Proper Barrier Function
Fig. 3.1 Chemical structures of the ceramides found in the human stratum corneum. S Sphingosine, P Phytosphingosine, H 6-Hydroxysphingosine, N non-hydroxy fatty acid, A alpha-hydroxy fatty acid, O ω-hydroxy fatty…
Formulation of Drug-Cyclodextrin Complexes
Cyclodextrin n R = H or Abbreviation Synonyms MSa MW (Da) Solubilityb (mg/ml) LogK o/w c α-Cyclodextrin 0 αCD Alfadex – 972.8 130 −13 β-Cyclodextrin 1 βCD Betadex…
Formulation Effects in Percutaneous Absorption
Fig. 9.1 Stratum corneum structure and main penetration pathways through skin (Adapted from Roberts et al. 2008) Penetrants may cross the skin using a number of routes, i.e. intercellular and…
Eutectic Systems for Penetration Enhancement
Fig. 12.1 Relationship between the steady-state flux of lidocaine and prilocaine through regenerated cellulose membrane and their solubility-normalized ratio in phosphate buffer solution: prilocaine (♦), lidocaine (□). Each point represents…
