Angiogenesis: General Concepts
Fig. 1.1 Morphological differences between capillary beds of various tissues. Confocal micrographs of blood vessels, shown in green, found in the retina, inner and outer choroid, skin, brain, heart, liver…
Infantile Hemangioma: New Insights on Pathogenesis and Beta Blockers Mechanisms of Action
© Springer-Verlag London Ltd. 2017Jack L. Arbiser (ed.)Angiogenesis-Based Dermatology10.1007/978-1-4471-7314-4_2 2. Infantile Hemangioma: New Insights on Pathogenesis and Beta Blockers Mechanisms of Action Shoshana Greenberger1 (1) The Department of Dermatology and Sheba Cancer Research Center, Sheba…
The Importance of Stratum Corneum Lipid Organization for Proper Barrier Function
Fig. 3.1 Chemical structures of the ceramides found in the human stratum corneum. S Sphingosine, P Phytosphingosine, H 6-Hydroxysphingosine, N non-hydroxy fatty acid, A alpha-hydroxy fatty acid, O ω-hydroxy fatty…
Formulation of Drug-Cyclodextrin Complexes
Cyclodextrin n R = H or Abbreviation Synonyms MSa MW (Da) Solubilityb (mg/ml) LogK o/w c α-Cyclodextrin 0 αCD Alfadex – 972.8 130 −13 β-Cyclodextrin 1 βCD Betadex…
Formulation Effects in Percutaneous Absorption
Fig. 9.1 Stratum corneum structure and main penetration pathways through skin (Adapted from Roberts et al. 2008) Penetrants may cross the skin using a number of routes, i.e. intercellular and…
Eutectic Systems for Penetration Enhancement
Fig. 12.1 Relationship between the steady-state flux of lidocaine and prilocaine through regenerated cellulose membrane and their solubility-normalized ratio in phosphate buffer solution: prilocaine (♦), lidocaine (□). Each point represents…
Thermosensitive Hydrogels in Dermatology: A Multidisciplinary Overview
Fig. 22.1 The hospital triad involved in dermatological medicine management and major outcome that should be considered by each protagonist Firstly, active pharmaceutical ingredients (APIs), currently prescribed by dermatologist, exhibit…
Skin Permeation: Enhancing Ability of Liquid Crystal Formulations
Scheme 17.1 A schematic representation of hexagonal phase Whereas cubic liquid crystals are formed when the concentration of micelles dispersed in a solvent is sufficiently high that they are forced…
The Effects of Emulsifiers and Emulsion Formulation Types on Dermal and Transdermal Drug Delivery
Fig. 16.1 Schematic illustration of breakdown processes of emulsions Emulsifiers are required for the formation of emulsions as they form a film around the newly formed drops and consequently prevent…
