Autoimmune connective tissue disorders Cutaneous lupus erythematosus Dermatomyositis Mixed connective tissue disease Nephrogenic fibrosing dermopathy Scleroderma (Systemic sclerosis) Autoimmune mucocutaneous blistering diseases Bullous pemphigoid Epidermolysis bullosa acquisita Lichen planus pemphigoides…
© Springer International Publishing Switzerland 2017Anthony A. Gaspari, Stephen K. Tyring and Daniel H. Kaplan (eds.)Clinical and Basic Immunodermatology10.1007/978-3-319-29785-9_46 46. Topical Immune Response Modifiers: Antiinflammatories Thomas A. Luger1 , Ian McDonald2 and Martin Steinhoff3 (1) Department of Dermatology, University Hospital Münster,…
© Springer International Publishing Switzerland 2017Anthony A. Gaspari, Stephen K. Tyring and Daniel H. Kaplan (eds.)Clinical and Basic Immunodermatology10.1007/978-3-319-29785-9_44 44. Therapy of Immunobullous Disorders Kyle Amber1 and Michael Hertl2 (1) Department of Dermatology, UC Irvine Health, Irvine, CA,…
© Springer International Publishing Switzerland 2017Anthony A. Gaspari, Stephen K. Tyring and Daniel H. Kaplan (eds.)Clinical and Basic Immunodermatology10.1007/978-3-319-29785-9_36 36. Epidermolysis Bullosa Acquisita Brittney De Clerck1, Mei Chen2 and David T. Woodley3 (1) Department of Dermatology, LAC & USC Medical Center,…
Fig. 30.1 Lupus-specific skin disease. (a) Acute cutaneous LE. (b) Drug-induced subacute cutaneous LE secondary to rabeprazole (Aciphex) (personal unpublished observation, R. D. Sontheimer). (c) Classical discoid LE affecting the…
© Springer International Publishing Switzerland 2017Anthony A. Gaspari, Stephen K. Tyring and Daniel H. Kaplan (eds.)Clinical and Basic Immunodermatology10.1007/978-3-319-29785-9_24 24. Immunology of Acne Galen T. Foulke1 and Amanda M. Nelson2 (1) Department of Dermatology, Pennsylvania State Hershey Medical Center, Hershey,…
Neuromediator Source Receptor Primary function Substance P Sensory nerve fibers Meissner corpuscles Perivascular nerves Mast cells Monocytes Eosinophils Tachykinin (neurokinin) receptor Mediates erythema and edema Increases histamine and TNF-α release…
Fig. 1.1 LC and DC populations in human skin. (a) LC and DC residing in human skin in the steady state and (b) infiltrating the skin during inflammation. The main…
JAML–CAR DETC express JAML (junction adhesion molecule like protein) at low level in steady state and upregulate its expression upon activation. The binding partner of JAML, the coxsackie and adenovirus…
TLR Disease Comments 1 Tuberculoid TLR1 favors Th1 phenotype [11] Leprosy TLR1 I602S mutation protects from M. leprae [12] Psoriasis TLR1 expression increased in keratinocytes [13] Lyme disease TLR1 polymorphism…
