Pathogenesis: Psoriasis is an autoimmune disease caused by an abnormality within the cells of the immune system. There is a genetic susceptibility, and the human leukocyte antigen (HLA) Cw6 locus…
Treatment: Therapy is directed at preventive care. Routine cardiovascular and ophthalmological examinations can help keep hypertension and early signs of retinal disease in check. Retinal hemorrhages need to be treated…
Treatment: The main treatment for PUPPP is to give supportive care and to try to suppress the itching symptoms. There are no ill effects on the fetus, and expectant mothers…
Treatment: The first-line therapy is with oral corticosteroids. The use of steroid-sparing agents early in the course of the disease may help decrease steroid-induced side effects. Cyclophosphamide is the major…
Treatment: Therapy for PRP is difficult. Many agents have been used with varying degrees of success. Topical corticosteroid wet wraps, oral retinoids, and ultraviolet therapy have long been used as…
Treatment: No therapy is needed. Most cases are asymptomatic and mild. Pruritus can be treated with oral antihistamines and adjunctive topical steroids. The use of oral erythromycin, twice a day…
Treatment: There is no agreed-upon standard therapy, and withholding therapy is a frequently used option. Anecdotally, topical corticosteroids may be tried for a few weeks. Oral vitamin C and bioflavonoids…
Treatment: Acute areas of involvement can be treated with topical corticosteroid creams. The main issue in management is dealing with the prolonged postinflammatory hyperpigmentation. No therapy has been shown to…
TTP is a rare, life-threatening disease that can develop rapidly. It is manifested by the formation of microthrombi throughout the small vasculature. This causes multisystem organ failure and rapid death…
Treatment: No known cure is available, and there is no effective therapy. Physical therapy and joint replacement increase flexibility and range of motion and help to decrease morbidity. Some researchers…
