Hydrogel Vehicles for Hydrophilic Compounds

Jul 8, 2017 by in Dermatology Comments Off on Hydrogel Vehicles for Hydrophilic Compounds

Fig. 20.1 Schematic representation of radical polymerization. Hydrogels are formed by the copolymerization of HEMA with EGDMA using AIBN as the radical initiator Fig. 20.2 Preparation of PVA hydrogels cross-linked…

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Transdermal Drug Delivery Systems Using Supersaturation

Jul 8, 2017 by in Dermatology Comments Off on Transdermal Drug Delivery Systems Using Supersaturation

Fig. 11.1 Diagram showing the critical degree of supersaturation (DS) and the different stability states of supersaturated systems The advantages of supersaturated systems for percutaneous penetration were first recognized by…

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Influence of Excipients on Two Elements of the Stratum Corneum Barrier: Intercellular Lipids and Epidermal Tight Junctions

Jul 8, 2017 by in Dermatology Comments Off on Influence of Excipients on Two Elements of the Stratum Corneum Barrier: Intercellular Lipids and Epidermal Tight Junctions

Fig. 7.1 In normal human skin (NHS), the SC may be subdivided into SC compactum, where the principal permeability barrier resides, and SC disjunctum, where the desquamation process takes place….

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Nanoemulsions in Dermal Drug Delivery

Jul 8, 2017 by in Dermatology Comments Off on Nanoemulsions in Dermal Drug Delivery

Fig. 18.1 (a) Optical appearance and cryo-TEM image of a translucent nanoemulsion (Reprinted from Sonneville-Aubrun et al. (2004), p. 146, with permission of Elsevier). (b) Cryo-TEM image of nano-sized oil…

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