Skin Basics; Structure and Function

Oct 15, 2016 by in Dermatology Comments Off on Skin Basics; Structure and Function

Fig. 2.1 Histology of pigmented skin, plastic embedded, semi-thick sections stained with Toluidine blue. (SB Stratum basale; SS Stratum spinosum; SG Stratum sranulosum; SC Stratum corneum) Stratum Basale (SB) The…

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Wax Esters: Chemistry and Biosynthesis

Oct 15, 2016 by in Dermatology Comments Off on Wax Esters: Chemistry and Biosynthesis

Fig. 11.1 Cytoplasmic malonyl-CoA decarboxylase assures that acetyl-CoA and methylmalonyl-CoA are the only substrate available for FAS The cytoplasmic malonyl-CoA decarboxylase has been purified, its cDNA has been cloned and…

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Skin Barrier, Structure, and Properties

Oct 15, 2016 by in Dermatology Comments Off on Skin Barrier, Structure, and Properties

Fig. 3.1 Historical timeline of skin barrier research. Adapted from Norlén (2013), with permission In the 1940s, Winsor and Burch (1944) showed, by sandpapering the skin surface, that the skin’s…

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Facial Subcutaneous Adipocytes

Oct 15, 2016 by in Dermatology Comments Off on Facial Subcutaneous Adipocytes

Fig. 14.1 Facial preadipocytes are more responsive to rosiglitazone-containing differentiation compositions, relative to abdominal preadipocytes. Human facial and abdominal preadipocytes in control media (CD, insulin, dexamethasone, and IBMX), or CD…

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The Brain of the Skin: Sebaceous Gland

Oct 15, 2016 by in Dermatology Comments Off on The Brain of the Skin: Sebaceous Gland

Fig. 8.1 Original figure of Günter Stüttgen’s publication (1964). adrenerg.  adrenergic, cholinerg.  cholinergic, Enzym. Akt. (Leber)  enzyme activity in the liver, Ganglien  ganglia, Gefässe  vessels, Haut skin, Keimdrüsen  sexual glands,…

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Acne and Lipid Pathways

Oct 15, 2016 by in Dermatology Comments Off on Acne and Lipid Pathways

Fig. 23.1 Sebaceous lipogenesis is dependent on the fatty acids available. While unsaturated ω3 and ω6 fatty acids are essential, ω9 can be synthetized by the sebaceous glands. The saturated/unsaturated…

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Atopic Dermatitis (AD) and Lipids

Oct 15, 2016 by in Dermatology Comments Off on Atopic Dermatitis (AD) and Lipids

Fig. 24.1 Structures and nomenclature of ceramides (CER) in human stratum corneum (SC). (Note: this research was originally published in J. Lipid Res. (Masukawa et al. 2008). © the American…

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Fats and Oils in Personal Care Products

Oct 15, 2016 by in Dermatology Comments Off on Fats and Oils in Personal Care Products

Count Chemical class Number of entries Sources 1 Complex lipids 74 Botanicals, animals, synthetics, and single-cell organisms 2 Essential oils 383 Botanicals 3 Glyceride esters 453 Botanicals, animals, synthetics, and…

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