Grading and Treatment of Acute Graft-Versus-Host Disease
Category Symptoms after DLI or HSCT Acute features Chronic features Classic acute < 100 days Yes No Persistent, recurrent and late-onset > 100 days Yes No Overlap > 100 days…
Overview of Hematopoietic Cell Transplantation
Fig. 1.1 Increasing numbers of patients are undergoing allogeneic hematopoietic stem cell transplantation (HSCT) every year (Adapted from Pasquini and Zhu [1]; with permission) Historical Perspective Pioneering experimentation by Jacobson…
Clinical Presentation of Mucosal Acute and Chronic Graft-Versus-Host Disease
Fig. 4.1 Ocular graft-versus-host disease. Ocular GVHD can affect almost every structure of the eye. Distinctive characteristics of chronic ocular GVHD include keratoconjunctivitis sicca, confluent areas of punctate keratopathy, and…
Pathophysiology and Immunology of Chronic Graft-Versus-Host Disease
Cell subset Risk of cGVHD References Effector memory CD4EM T cells (CCR7neg CD62Llow) Increase in this T-cell subset co-related with increased risk of cGVHD Yamashita et al. [7] CD8+ Central…
