Treatment: Isolated lesions can be treated with topical corticosteroids. Up to two thirds of skin lesions resolve spontaneously. Patients with widespread disease present a therapeutic challenge. Ultraviolet phototherapy, oral corticosteroids,…
Treatment: Therapy is often directed at breaking the itch-scratch cycle. This is attempted with a combination of topical high-potency corticosteroids and oral antihistamines or gabapentin. The sedating antihistamines work better…
Treatment: Therapy is based on the cause of the leukocytoclastic vasculitis. New offending medications should be withdrawn and replaced with substitutes of a different class. Infections need to be thoroughly…
Multisystem disease is treated in myriad manners, depending on the burden of disease, the systemic involvement, and the patient’s symptoms. The disease can be difficult to treat, and systemic chemotherapies…
Treatment: No therapy is required for most cases. A keratolytic moisturizer or humectant moisturizer works well. These include lactic acid– and salicylic acid–based moisturizers. After discontinuation, however, the rash of…
Twenty percent of patients do not exhibit any cutaneous signs of disease and present solely with varying systemic complaints. The most common extracutaneous form of LCH, formerly designated eosinophilic granuloma,…
Treatment: The goal of treatment is to remove the skin from exposure to the irritant. Barrier creams and frequent diaper changes may be all that is needed to resolve irritant…
Treatment: Therapy is often aimed at reducing inflammation and bacterial superinfection. There is no curative therapy, and most treatments have only anecdotal reports of success. Topical clindamycin and other antibacterial…
Treatment: Treatment of Graves’ disease is predicated on stopping the excessive thyroid hormone production. Ablation of the thyroid can be achieved with radiation therapy or surgical removal. Medications such as…
Treatment: Localized forms of granuloma annulare that are asymptomatic and not causing any distress to the patient can be left alone. Most cases resolve spontaneously over time with no residual…
