Microporation Using Microneedle Arrays

Oct 14, 2017 by in Dermatology Comments Off on Microporation Using Microneedle Arrays

Fig. 18.1 Approaches aiming at facilitation of peptide/protein transport across the skin This chapter will focus on the use of microneedle (MN) arrays as medical devices to disrupt the barrier…

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Magnetophoresis: Skin Penetration Enhancement by a Magnetic Field

Oct 14, 2017 by in Dermatology Comments Off on Magnetophoresis: Skin Penetration Enhancement by a Magnetic Field

Magnet characteristics Experimental model Compound applied Passive permeation μg/cm2/h Magnetophoretic permeation μg/cm2/h Enhancement ratio References Permanent magnets (0.01–0.05 mT) Excised abdominal skin of albino rats Benzoic acid (saturated solution)   ≈1.8–2.6…

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The Synergistic Effect of Iontophoresis or Electroporation and Microneedles on the Skin Permeation of High Molecular Weight Compounds

Oct 14, 2017 by in Dermatology Comments Off on The Synergistic Effect of Iontophoresis or Electroporation and Microneedles on the Skin Permeation of High Molecular Weight Compounds

Fig. 24.1 Schematic illustration of microneedle array made by acupuncture needles. (a) Top view, (b) back view, (c) one needle. Each needle tapered over a 400-μm length to a sharp…

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Fabrication of Microneedles

Oct 14, 2017 by in Dermatology Comments Off on Fabrication of Microneedles

Physical vapor deposition (PVD) techniques Chemical vapor deposition (CVD) techniques Others deposition techniques Thermal evaporation Plasma-enhanced CVD (PECVD) Epitaxy Sputtering Atmospheric pressure CVD Casting Molecule beam epitaxy Low pressure CVD…

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