Fig. 12.1 Demonstration of the pathogenicity of anti-COL7 autoantibodies in vitro, ex vivo, and in vivo. (a) Schematic diagram of reactive oxygen species (ROS) induced by immune complexes (IC) generated…
Fig. 40.1 Characteristic cutaneous lesions on trauma-prone surfaces in a classical form of EBA: (a) tense bullae on normal skin of an ankle, (b) few post-bullous erosions on the back…
Skin Clinical features Blisters, nail dystrophy, sparse hair Immunomapping Focal disruption of the dermo-epidermal junction, cleavage within the plane of the basement membrane Transmission electron microscopy Thin lamina densa, discontinuous…
© Springer-Verlag Berlin Heidelberg 2015Dédée F. Murrell (ed.)Blistering Diseases10.1007/978-3-662-45698-9_76 76. Future Therapies for Epidermolysis Bullosa Jaehwan Kim1, 2 , Wenfei Yan2 and Dédée F. Murrell2 (1) Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA (2) Department…
© Springer-Verlag Berlin Heidelberg 2015Dédée F. Murrell (ed.)Blistering Diseases10.1007/978-3-662-45698-9_75 75. The Pathogenesis and Management of Pruritus in Epidermolysis Bullosa Frank P. Brennan1 (1) Department of Palliative Care, St. George Hospital, Sydney, NSW, Australia Frank P. Brennan…
Fig. 28.1 Transmission electron microscopy of a desmosome and schematic representation of the main molecular components Genetic disorders affecting the desmosomal assembly, structure or integrity disrupt not only the intercellular…
Type of dressing Common brands Foams Mepilex and Mepilex Lite (Molnlycke), PolyMem (Ferris Mfg) Modified absorbent pads Telfa (Kendall Comp Ltd), Restore (Hollister), ETE (Molnlycke), Mesorb (Molnlycke) Lipidocolloid dressings Urgotul…
© Springer-Verlag Berlin Heidelberg 2015Dédée F. Murrell (ed.)Blistering Diseases10.1007/978-3-662-45698-9_69 69. The Pathogenesis, Assessment and Management of Pruritus in Autoimmune Bullous Diseases Frank P. Brennan1 , Chris H. L. Lim2 and Dédée F. Murrell3 (1) Department of Palliative Care, St George Hospital, Sydney,…
© Springer-Verlag Berlin Heidelberg 2015Dédée F. Murrell (ed.)Blistering Diseases10.1007/978-3-662-45698-9_66 66. Management of Erythema Multiforme, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Benjamin S. Daniel1 , Pascal Joly2 and Dédée F. Murrell3 (1) Department of Dermatology, St. George Hospital, Sydney, NSW, Australia…
© Springer-Verlag Berlin Heidelberg 2015Dédée F. Murrell (ed.)Blistering Diseases10.1007/978-3-662-45698-9_67 67. Quality of Life in Autoimmune Blistering Diseases Giuseppe Cianchini1 , Andrea Paradisi2 and Dédée F. Murrell3 (1) 3rd Division of Dermatology, Center for Autoimmune Bullous Diseases, Istituto Dermopatico Dell’immacolata,…
