Lipophilic Antioxidants
Boelsma E, Hendriks HF, Roza L. Nutritional skin care: health effects of micronutrients and fatty acids. Am J Clin Nutr. 2001;73:853–64.PubMed Braun L, Cohen M. Herbs and natural supplements-an evidence…
Mineral Oil in Skin Care: Safety Profile
Species No of animals Duration Material Dose mg/kg/day Results C3H/HeJ mice 50 3 × per week over lifetime White oil 296 No histopathological changes, no tumors C3H/HeJ mice 50 3 × per…
PPAR Gamma Receptor, Skin Lipids and Hair
Barak Y, et al. PPAR gamma is required for placental, cardiac, and adipose tissue development. Mol Cell. 1999;4(4):585–95.PubMedCrossRef Berger H, et al. SOCS3 transactivation by PPARgamma prevents IL-17-driven cancer growth….
Triglyceride Synthesis Enzymes in Skin/Fur
Fig. 16.1 Acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes and triacylglycerol (or triglyceride) biosynthesis. There are two major pathways for triacylglycerol synthesis: the glycerol phosphate pathway (or Kennedy pathway) and the monoacylglycerol pathway….
Stearoyl-CoA Desaturases are Regulators of Lipid Metabolism in Skin
Bonet ML, Ribot J, Felipe F, Palou A. Vitamin A and the regulation of fat reserves. Cell Mol Life Sci. 2003;7:1311–21.CrossRef Cases S, Stone SJ, Zhou P, Yen E, Tow…
Adipose Tissue and Fat Cell Biology
Brooks BJ. Studies on the triglyceride—fatty acid cycle. Oxford: Merton College; 2013. Brown NF, Hill JK, Esser V, Kirkland JL, Corkey BE, Foster DW, McGarry JD. Mouse white adipocytes and…
Squalene Chemistry and Biology
Fig. 12.1 Linear (Ia) and folded (Ib) structures of squalene (I) and structure of 2,3-oxidosqualene (II, squalene epoxide). Squalene is transformed into several oxygenated derivatives and breakdown compounds by different…
Sebaceous Lipids
Lipid class Range weight, % Mean weight, % Triglycerides 20–60 45 Wax esters 23–29 25 Squalene 10–14 12 Free-fatty acids 5–40 10 Cholesterol and sterol esters 1–5 4 Diglycerides 1–2…
Nuclear Hormone Receptors and Epidermal Differentiation
Fig. 7.1 Keratinocyte differentiation involves changes in the protein and lipid composition of different epidermal layers. Epidermal proliferation and differentiation are essential for the formation of the cornified layer and…
Skin Lipids: An Introduction and Their Importance
© Springer Science+Business Media New York 2015Apostolos Pappas (ed.)Lipids and Skin Health10.1007/978-3-319-09943-9_1 1. Skin Lipids: An Introduction and Their Importance Apostolos Pappas1 (1) The Johnson & Johnson Skin Research Center, CPPW, a division of Johnson…
