Acne Variants
Many other treatment options exist, including topical agents such as azelaic acid, adapalene, tazarotene, salicylic acid, and topical antibiotics. Oral medications that can be used include multiple oral antibiotics, spironolactone,…
Acne Vulgaris
Rare forms of acne include acne fulminans, acne conglobata, and acne aestivalis. Acne fulminans is seen almost exclusively in teenage boys. It is a form of severe cystic nodular acne…
Squamous Cell Carcinoma: Clinical and Histological Evaluation
Metastatic SCC of the skin should be treated with adjunctive radiotherapy and chemotherapy. However, these therapies have not shown a clear survival benefit, and the key to treatment ultimately lies…
Acanthosis Nigricans
Treatment of malignancy-associated acanthosis nigricans is directed at the underlying malignancy. Removal of the tumor may result in complete resolution of the skin disease. Related posts: Skin Physiology—The Process of…
Squamous Cell Carcinoma: Genital Squamous Cell Carcinoma
A few chronic dermatoses can predispose to the development of SCC, including lichen sclerosis et atrophicus, disseminated and superficial actinic porokeratosis, warts, discoid lupus, long-standing ulcers, and scars. Many genetic…
Sebaceous Carcinoma
Histology: These tumors are derived from sebaceous glands and show a high degree of infiltrative growth. The tumor deeply invades the subcutaneous tissue; in the periocular area, it often invades…
Mycosis Fungoides: Histological Analysis of Cutaenous T-Cell Lymphoma
Despite the many therapies available, no treatment has been shown to increase survival in patients with mycosis fungoides. It is therefore inadvisable to treat stage IA disease with a medication…
Mycosis Fungoides: Clinical Subtypes of Cutaneous T-Cell Lymphoma
At the other end of the spectrum is the Sézary syndrome. This is an erythrodermic variant of mycosis fungoides with peripheral blood involvement. Circulating Sézary cells are the hallmark of…
Melanoma: Metastatic Melanoma
Sentinel lymph node sampling is becoming routinely performed in the care of these patients and aids in staging of the disease. If the patient has a positive sentinel lymph node…
Merkel Cell Carcinoma
Histology: Merkel cell carcinoma is a neuroendocrine tumor. The tumor is composed of small, uniformly shaped, basophilic-staining cells. The tumor is poorly circumscribed and grows in an infiltrative pattern between…
