Kaposi Sarcoma



Kaposi Sarcoma


Elyse M. Love

Evan Rieder



BACKGROUND

Kaposi sarcoma (KS) is a multifocal cutaneous disease of multiple variants that affects endothelial cells.


PRESENTATION

Patients present with slow-growing, pink to red to violaceous macules on the lower extremities. Patients may have a history of immunosuppression, AIDS, or Mediterranean or African heritage.




PATHOGENESIS

All clinical variants are all understood to be secondary to viral activation of HHV-8. It remains unclear whether KS represents a neoplasm or hyperplasia of endothelial cells. It is also unclear if affected endothelial cells are vascular, lymphatic, or a mixture of the 2 types.1

Jun 29, 2020 | Posted by in Dermatology | Comments Off on Kaposi Sarcoma
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