Dermatology: Fillers, Neurotoxins, and Chemical Peels

, Julie Karen1 and Perry Robins1



(1)
New York University School of Medicine, New York, NY, USA

 






Table 4.1
Botulinum toxin dilutions
































Amount of saline used for dilution (mL)

Units of Botox® per 0.1 cc (U)

Common indications

1

10
 

2

5

Facial rhytides

2.5

4

Facial rhytides

4

2.5

Axillary hyperhidrosis (usual dose 100 U)

5

2

Axillary hyperhidrosis


Notes:

• Mechanism of action: inhibits acetylcholine (ACh) release by cleaving proteins in the SNARE complex required for ACh release

• Dilution should be performed with 0.9 % normal saline

• One unit of Botox® is approximately equivalent to 2.5–3 units of Dysport® (abobotulinum toxin A)

• One unit of Botox® is approximately equivalent to 1 unit of Xeomin® (incobotulinum toxin A)



Table 4.2
Injectable fillers


























Filler

Duration

Derivation

Comments

Alloderm®

Months to years

Acellular human cadaveric dermis

Surgically implanted in sterile filed

Artecoll®a,  Artefil®

Permanent (>5 years)

PMMAb beads in bovine collagen, allergy test required

Injected deeper than collagen

LaViv®a

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Apr 1, 2017 | Posted by in Dermatology | Comments Off on Dermatology: Fillers, Neurotoxins, and Chemical Peels
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