Fig. 43.1
PC-RMS is a multinodular proliferation of atypical round or spindle cells centered in the dermis and/or subcutis
Fig. 43.2
The tumor cells are arranged in nodules and sheets without epidermal involvement
Fig. 43.3
The alveolar subtype is composed of aggregates of “small round blue” cells divided by thick fibrous septa. Central discohesion of tumor cells is often present resulting in an “alveolar” appearance
Fig. 43.4
In the alveolar subtype, the tumor nuclei are relatively uniform and monotonous
Fig. 43.5
The embryonal subtype displays hyperchromatic ovoid cells admixed with scattered rhabdomyoblasts with abundant eosinophilic cytoplasm
Fig. 43.6
The pleomorphic subtype is composed of sheets of pleomorphic spindle cells, some of which have eccentrically located atypical nuclei and abundant dense eosinophilic cytoplasm
Fig. 43.7
The epithelioid subtype is composed of pleomorphic round epithelioid cells with abundant dense eosinophilic cytoplasm