A 25-year-old female patient presented with sequelae of left-sided facial paralysis (Fig. 15.1). This patient was treated with a combined procedure carried out in 1986, which included: (1) suspension of the left hemiface with flaps without dermal epithelium; (2) selective myectomies in the right melolabial sulcus, removing the following muscles – canine tooth, zygoma, risorius, triangularis, and quadratus bottom; (3) segmental rhytidoplasty; and (4) lipo-injection of 40 mL in the following areas: upper lip of the left side, left cheek, and zygomatic region and subsequently lipo-injection of 10 mL every 6 months on four occasions. The aesthetics of the patient’s improvement were very noticeable, and there was a high degree of regeneration in the motor muscle innervation, seeing the patient 2 years later (Fig. 15.1), 8 years later (Figs. 15.5 and 15.6), and 20 years later (Fig. 15.1) [3].

A 33-year-old female patient presented sequelae of facial paralysis in the right side of her face and aesthetic and functional deformity on the lips of the right side (Fig. 15.2). This patient was treated with only four sessions of lipo-injection introducing every 6 months fat grafts of 6 mL on the upper lip and 4 mL lower lip. There were excellent results both aesthetic and functional (Fig. 15.2).