Primary Cutaneous Rhabdomyosarcoma



Fig. 43.1
PC-RMS is a multinodular proliferation of atypical round or spindle cells centered in the dermis and/or subcutis



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Fig. 43.2
The tumor cells are arranged in nodules and sheets without epidermal involvement


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Fig. 43.3
The alveolar subtype is composed of aggregates of “small round blue” cells divided by thick fibrous septa. Central discohesion of tumor cells is often present resulting in an “alveolar” appearance


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Fig. 43.4
In the alveolar subtype, the tumor nuclei are relatively uniform and monotonous


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Fig. 43.5
The embryonal subtype displays hyperchromatic ovoid cells admixed with scattered rhabdomyoblasts with abundant eosinophilic cytoplasm


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Fig. 43.6
The pleomorphic subtype is composed of sheets of pleomorphic spindle cells, some of which have eccentrically located atypical nuclei and abundant dense eosinophilic cytoplasm

Oct 15, 2016 | Posted by in Dermatology | Comments Off on Primary Cutaneous Rhabdomyosarcoma

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