8 Use of Light- and Energy-Based Therapies with Cosmetic Surgery Summary Perceived aesthetic appearance is based in part on the amount of redundant skin, the impact of the underlying supporting structures, and the quality of the skin itself. Normal aging changes such as hyperpigmentation and hypopigmentation, hypervascularity, fine wrinkles, skin laxity, and skin pore size and texture can be treated with light- and energy-based therapies (LAEBT) with high patient satisfaction. Keywords: ablative therapy, aging process, carbon dioxide (CO2), chromophore, erbium, hyperpigmentation, hypervascularity, hypopigmentation, ionizing radiation, light- and energy-based therapy (LAEBT), nonablative fractional resurfacing, photorejuvenation, radiofrequency (RF), skin damage, supplements Key Points • What defines a youthful appearance? How can providing patients ancillary light- and energy-based therapies (LAEBT) result in a more complete aesthetic improvement? • Patient selection and skin analysis is critical to obtain good outcomes. • Understanding the limitation of one’s device is important. • Thermal energy and resultant dermal heating is responsible for skin tightening. Which patients are ideal for treatment with these modalities? How can the clinician optimize patient safety and outcomes? • When using LAEBT, complications can be minimized by initially using manufacturers, device settings, and staying upto-date by attending certified, CME education courses. One’s perceived aesthetic appearance is based in part on the amount of redundant skin, the impact of the underlying supporting structures, and the quality of the skin itself. Although surgeons often focus on the skin envelope and supporting structures, the remaining skin has changed from its original, youthful manifestation. Signs of this change are evident through undesirable hyperpigmentation and hypopigmentation, hypervascularity, fine wrinkles, and items difficult to quantify such as skin pore size and texture ( Fig. 8.1). To date, light- and energy-based therapies (LAEBT) have not been shown to provide skin tightening that parallels the results obtained through surgery. However, LAEBT can significantly improve patient satisfaction regarding their appearance after surgery. They also provide nonsurgical options, which would allow the treating clinician to improve the patient’s appearance. The etiology of the signs of skin aging is multifactorial. An acknowledged source of skin damage is the effect of ionizing radiation from the sun. Despite medical advice, many patients still do not wear sunscreen or do not apply them as directed. The cumulative impact of the sun’s radiation on unprotected skin can cause dyschromia.1 A genetic component also factors into one’s aging process. Not all individuals age the same way given parallel environmental exposure. Systemic conditions such as diabetes, scleroderma, or other connective tissue disorders impact the appearance of one’s skin and the ability to heal.2 Cystic acne during adolescence can leave scars that may become more unsightly as one ages.3,4 Hormonal changes can affect the appearance of an individual’s skin.5 Even one’s lifestyle beyond the harmful effects of the sun’s radiation can impact the aging process of the skin. Smoking is harmful to the skin and wound healing.6 Proper skin hygiene can mitigate the signs of aging by keeping skin pores open and minimizing unwanted melanin in the epidermis. Individuals trying to optimize the appearance of their skin spend millions of dollars using over-the-counter, topical agents that do not have peer review papers substantiating their efficacy. Fig. 8.1 This is a good representation of a graphic example of the difference between younger and older skin. There are many factors that influence the outcome of nonsurgical LAEBT results. To actualize the patient’s expectations requires effective communication between the clinician and patient. Selecting the correct LAEBT to address the patient’s concern is predicated upon proper patient selection and understanding the limitations and capabilities of one’s device. If a patient has unrealistic expectations, then the final outcome could be compromised regardless of the skin treatment therapy utilized. When providing treatment alternatives, it is better to underpromote than to deal with the perceived promises that may not be fulfilled. A comprehensive informed consent and written pretreatment and posttreatment instructions can mitigate posttreatment misunderstandings. Many LAEBTs rely on the energy being focused to a chromophore, which can be water, melanin, and/or hemoglobin ( Fig. 8.2). When a patient presents with a “tan,” they should be given the option to wait until the tan fades before initiating treatment if the energy source efficacy is impacted by skin color. This way, the energy that is intended for undesirable melanin will not be drawn to the skin pigment because of the transient tan. Patients with hypervascularity should be advised to avoid anything that would cause vasodilatation prior to treatment. If a patient has a hypersensitivity to sunlight, using a device that provides light energy as a therapeutic modality should not be recommended.2 Patients who have taken recent medications such as isotretinoin or oral antibiotics, which are known to cause hyperpigmentation, should have their aesthetic treatment delayed until the systemic effects of these medications have expired. Even nonprescribed medications such as St. John’s Wort can negatively impact the final outcome, because the use of such a nonprescribed medication can contribute to hyperpigmentation. Prescribed medications such as Coumadin (warfarin, Bristol-Myers Squibb Company) or over-the-counter medications that impact the coagulation cascade should be stopped prior to treatment if it would not compromise the patient’s health to minimize the potential complication of bruising ( Table 8.1 and Table 8.2). Pregnancy is a “relative” contraindication. Most companies have not performed studies that demonstrate safety in such a clinical setting. Patients with active autoimmune or connective tissue disorders should not be treated.7 However, patients with stable lupus may still have unwanted skin redness once their condition becomes stable and they are not receiving treatment for their medical condition. Good results can be obtained in terms of improving residual hypervascularity. Table 8.1 Medications that may complicate LAEBT*
8.1 Introduction
8.2 Patient Selection
8.2.1 Safety
Acelite | Actifed | Advil |
Alka Seltzer | Aleve** | Anacin |
Anaprox** | APC Tablets | A.R.M. |
Arthritis Pain Tabs** | Ascodeen | Ascriptin** |
Asperbuf** | Aspergum** | Aspirin** |
Aspirin Suppository | Axotal | Baby Aspirin** |
Bayer** | Bismol | Buff A Comp Tabs |
Bufferin | Clinoril** | Celebrex** |
Congespirin | Contact | Cope |
Coricidin D Decongestant | Coricidin Tablets | Cospirin |
Coumadin | Darvon With Aspirin | Dolobid |
Caspirin | Emprazil | Emperin With Codeine |
Equagesic | Excedrin** | 4-Way Cold Tablets |
Feldene | Fiorinal | Fiorinal With Codeine |
Gemnisyn | Hyco Pap | Ibuprofen** |
Indocin | Indomethacin | Nurofen** |
Medigesic Plus Caps | Medpro Compound Tabs | Midol |
Monacet | Motrin** | Naprosyn** |
Norgesic | Norgesic Forte | Orudis** |
Pabirin | Panalgesic | Pepto Bismol |
Percodan | Rhinex | Rufen |
Sk-65 | Sudafed | Supac |
Synalgos | Talwin | Vanquish |
Vioxx** |
|
|
*When taken 2 weeks before surgery
**Or any type of anti-inflammatory medication
The treatment of patients with a history of wound-healing problems, such as keloid and hypertrophic scarring, needs to be evaluated to determine why such conditions occurred. Hypertrophic scarring can occur after burn injuries and can be improved with ablative technology and or pulsed light treatments.8 Potentially cancerous skin lesions in the treatment area should be biopsied prior to addressing aesthetic concerns. In contrast, benign conditions such as actinic keratosis can be treated with LAEBT, cryotherapy, or other modalities.
As part of patient safety, topics to include in an informed consent for LAEBT are prolonged redness, transient “speckling” (hyperpigmentation), scabbing, edema, hair loss, purpura, hyperpigmentation, hypopigmentation, bruising, activation of a cutaneous herpetic skin eruption, infection, scarring, and dissatisfaction. In general, the more ablative the device, the greater the potential for these adverse side effects.
Table 8.2 Supplements that may impact LAEBT adversely*
Arnica montana (unless prescribed) | Bilberry |
Cayenne | Don quai |
Echinacea | Feverfew |
Fish oil | Garlic |
Ginger | Ginkgo biloba |
Ginseng | Hawthorne |
Kava kava | Licorice root |
Ma huang (ephedra) | Melatonin |
Red clover | St. John’s wort |
Valerian | Vitamin E |
Yohimbe |
|
*When taken 2 weeks before surgery
8.2.2 Analysis of the Skin
It is very important to address the individual’s skin color. The gold standard for rating skin color is the Fitzpatrick scale7( Fig. 8.3). Patients with a lighter skin color (Fitzpatrick I–III) are easier to treat when dealing with dyschromia, because the adjacent, untreated skin does not have as much innate pigment, allowing for an easier “blending” to the untreated region. Patients with Fitzpatrick skin types IV–VI can be treated successfully with LAEBT. To minimize the chance of posttreatment hyperpigmentation, these patients should be pretreated with a bleaching cream such as hydroquinone or kojic acid.8 These topical agents should be continued until the patient has obtained his or her optimized, final skin color. Patients with a history of herpetic skin breakouts in the treatment area should be prescribed antiviral medication, which should be continued until the patient has fully recovered.
Determining the basis of the dyschromia is a critical component to providing optimal care. Hyperpigmentation is the most common manifestation of the aging process of the skin; this can consist of isolated spots or an overall yellow or brown discoloration on the skin. When hyperpigmentation manifests as overall yellow or brown skin discoloration, it can hinder identifying the underlying hypervascularity as the redness is camouflaged. Reducing the undesirable brown skin discoloration will reveal this vascular problem. Thus, a thorough evaluation of the skin regarding the desired improvement in hyperpigmentation, hypervascularity, and skin wrinkling is needed prior to selecting the best modality for treatment.
It is important to appreciate the various densities of the undesirable chromophore or skin rhytides, which can vary within the treatment region. Patients with rosacea often have a prominence of hypervascularity in the malar region. Not adjusting device parameters in response to chromophore density may result in a complication or inadequate results. The perioral and orbital regions are often left with skin wrinkles after a successful surgical procedure. Ablative energy may reduce these signs of aging. To optimize ablative therapy in areas with deeper skin wrinkles, a second or third pass is often needed.
The patient’s age also can influence the treatment parameters and outcome. Parameters successfully used treating individuals in their thirties may need to be adjusted for those who are 50 to 60 years of age due in part to a thinning of the dermis, wound healing, and concomitant medical conditions.
The location of the treatment is also an important consideration. Although the desired results are similar to those for facial skin, the device settings used for facial skin may need to be adjusted when treating the skin on the neck, chest, or hands. Depending on the technology used, the recovery process can be more difficult when treating nonfacial skin.9
8.2.3 Understanding the Technology
There are many LAEBT that can improve the appearance of the skin. Each manufacturer has enabled its device with unique features, which prevents the clinician from transferring specific treatment parameters from one manufacturer’s device to another’s manufacturer’s device despite using the same type of therapeutic energy. Thus, the operator must have a thorough understanding of how the device settings can impact the final result. Variables that impact outcomes include but are not limited to the type of energy, number of treatments, wavelength, fluence, density pattern, overlapping of pulses, and number of “passes.” Adequate training is imperative when incorporating LAEBT into one’s practice. Using treatment parameters within the manufacturers guidelines is the best way to minimize complications.
8.2.4 Combining Modalities
As clinicians understand LAEBT, their limitations, and how to avoid complications, combining different modalities may enhance outcomes. Photorejuvenation following ablative therapy can be helpful with blending to adjacent skin areas. Providing radiofrequency (RF) treatments to the perioral or periorbital regions can smooth skin wrinkles following the improvement in dyschromia through photorejuvenation.10,11 During the recovery process after ablative therapy, affording patients photorejuvenation treatments with the fluence reduced and selecting a cutoff filter that delivers energy primarily directed toward red can shorten the recovery time.
8.3 Pretreatment and Posttreatment Protocols
Although the clinician should use his or her judgment as to what protocol to follow, the following guidelines are helpful when using LAEBT regardless of the specific device.
Prior to Treatment
• Avoid medications with anticoagulant effects.
• Avoid medications that are known to create hyperpigmentation.
• Avoid high-dose topical Vitamin C and retinoids 1 week prior to treatment.
• Stress the importance of applying topical sun blocks during therapy.
• Recommend topical pretreatment and posttreatment of bleaching creams for IV skin types.
• Advise patients who receive routine skin treatments from their esthetician to avoid chemical peels or vigorous extractions during the course of LAEBT.
• Stress the importance of the prophylactic use of antiviral medication if the patient has a history of herpetic skin eruptions.
• Ensure that there is enough time for the medication to work prior to LAEBT treatment if a topical anesthetic cream is to be used for pain control.
• Provide protective eyewear during treatment.
8.4 Incorporating Nonsurgical LAEBT
There are many pathways to improve the appearance of the skin using LAEBT. Providing patients these types of opportunities should enhance their overall aesthetic experience. Given the gamut of nonsurgical techniques currently available, it is impossible to demonstrate the efficacy of all therapies. The cases presented reflect some of the possible nonsurgical options in which the appearance of the skin is improved and embraces a more complete rejuvenation result (see Video 1.1).
8.4.1 Ablative Therapy
Prior to the early 1990s, chemical peels and dermabrasion were the mainstay of topical, nonincisional treatment for wrinkles and unwanted brown spots. These modalities are still used effectively. The implementation of lasers to treat hyperpigmentation and skin wrinkling became popular in the early 1990s.8Usually lasers provide a single, collimated wavelength delivered to the skin. The primary wavelengths used for laser skin resurfacing are CO2 (10,600 nm) or erbium YAG (2,940 nm). The dynamic ability to control the depth of injury through the device settings during treatment enhanced the use of lasers compared to topical chemical agents. The “target” of the energy is the water content within the skin. The evolution of laser therapy has been focused on minimizing the recovery period by reducing the initial zones of injury. Providing smaller focal injury spots and delivering laser energy in a scattered pattern has helped shorten recovery times and treatment discomfort. This modification may require more than one treatment to provide parallel results, however. Depending on the amount, density, and pattern of the energy delivered, lasting results may be seen after one to three treatments. In general, the greater the energy delivered and the higher the density, the longer the recovery for each treatment ( Fig. 8.4). The end point for a fully ablative single treatment is a light tan skin color. When providing less energy to the skin, hyperemia may reflect the desired initial skin reaction.
Initial recovery times can be short, 2–3 days or longer, for 3–8 weeks. Multiple laser treatments may be required when patients opt for shorter recovery periods. Typically, there is some initial skin crusting, because the energy penetrates into the dermis and ablates tissue within the zone of injury. Post-treatment protocols may parallel the protocols provided to individuals with second-degree burns, including topical creams and or bandages. Camouflage makeup can be applied once the skin is healed. Treatment analgesia is customized to the fluence, the density of the energy delivered, and the energy wavelength, and it can range from topical analgesics with oral supplementation to general anesthesia.
In terms of the wavelengths for each laser, it is CO2 or erbium for the fully ablative image, erbium for the nonablative fractional resurfacing, and CO2 for the ablative fractional resurfacing. The ideal patient does not have underlying redness but is looking for an improvement in skin wrinkling and hyperpigmentation. Removing the undesirable “brown” skin color may reveal pre-existing redness that was masked by the unwanted melanin in the epidermis. Because of the potential for hypopigmentation posttreatment, treating patients with Fitzpatrick skin type IV–VI requires a modification of one’s protocol for treating skin types II–III. Being able to “blend” the treated area to the adjacent skin by altering the energy settings or delivery pattern is important. The need to adjust the pattern and amount of energy delivered also needs to be considered when treating regional areas, such as the perioral and periorbital regions, which are often left with wrinkles following a rhytidectomy or blepharoplasty.
Clinical Results
This woman had a facelift performed by another physician. Her concerns were the residual fine wrinkling and brown spots on her face ( Fig. 8.5a). She underwent full-face, CO2 laser skin resurfacing. The clinical end point of laser treatment on the deep wrinkles was a chamois color of the skin. Other regions without such deep wrinkles had skin erythema as the treatment end point. Two years after this treatment, this woman had smoother skin and a reduction in her hyperpigmentation ( Fig. 8.5b). As she continued to age, she received periodic neurotoxin injections on her forehead and in the lateral orbital and perioral regions. She has maintained an improvement in her skin color and wrinkle reductions using this protocol, as shown 5 years ( Fig. 8.5c) and 10 years ( Fig. 8.5d) after her ablative treatment.