Lipotransfer represents a technical revolution in plastic surgery and is increasingly used worldwide. Although known for several decades, lipofilling has only recently found widespread use in patients with breast cancer to improve the results of breast reconstructions and to correct deformities after conservative treatment. The plastic surgery literature underlines the technique’s versatility and the quality of the results, showing lipofilling as an effective cosmetic procedure and proposing it as a safe, neutral biological material that is able to restore the body contour. Several studies underline the power of transferred fat to regenerate blood supply in skin disorders following radiotherapy.
Key points
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Biological considerations: review of experimental research and translational studies.
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Technique: differentiate the transfer technique with simple purification of the fat or an enrichment technique.
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Clinical evaluation based on a reliable statistical method to limit the risk of bias.
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Randomized trial is the best method but is not realistic in plastic surgery indications (patients refuse to submit to the surgeon choice).
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Prospective studies are more reliable than retrospective studies but require long accrual periods.
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Prospective or retrospective studies should at least be case-control studies.
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Definitive conclusions require large series, control groups with a rigorous matching of the cancer criteria, and at least 5 years’ mean follow-up.
Related posts:
Fat Grafting for Facial Filling and Regeneration
Primary Breast Augmentation with Fat Grafting
Combined Use of Implant and Fat Grafting for Breast Augmentation
Regenerative Approach to Velopharyngeal Incompetence with Fat Grafting
Regenerative Approach to Scleroderma with Fat Grafting
Percutaneous Aponeurotomy and Lipofilling (PALF)
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