Hip Arthroplasty in Severe Deformity

   Severe deformity is a congenital (acquired or iatrogenic) abnormality in the size and shape of the native acetabulum or proximal femur, and special techniques or implants must be employed by the surgeon to perform a primary total hip arthroplasty (THA).


ANATOMY


   Severe deformities around the hip typically result from pediatric hip disease, skeletal dysplasia, infection, metabolic bone disease, or trauma; or are the consequences of the treatment.


   The American Academy of Orthopaedic Surgeons’ classification can be used to describe both acetabular-sided11 and femoral-sided12 deformity:


   Acetabular deficiencies in deformity are frequently segmental (type I), cavitary (type II), or combined (type III).

   Femoral abnormalities are typically malalignment (type IV) or stenosis (type V). The Paprosky classification does not include these deformities. However, occasionally, the proximal femur is completely absent.

   Although we focus on bony abnormality because of technical problems with fit and fix, deformed anatomy around the hip also alters local hip biomechanics with subsequent overloading and secondary osteoarthritis (OA) because of changes in the insertion and lever arm of muscles around the hip, particularly the abductors.


   Deformed anatomy at the hip affects the mechanical alignment of the entire lower limb and alters the biomechanics of the knee, ankle, and foot, and can lead to degenerative joint disease at these locations.


   Abnormal anatomy creates difficulties in approach (identifying true anatomy), implant selection (because of problems with endosteal anatomy), size, and the challenges of restoring lower limb biomechanics.


   The most common cause of hip deformity in adults is developmental dysplasia of the hip (DDH), where a small dysplastic acetabulum is coupled with an anteverted femur with a narrow canal which may have been treated with previous proximal femoral osteotomy, further complicating the deformity. DDH itself can be caused by congenital dysplasia (most commonly dislocation), the consequences of infantile infection, neuromuscular disease, or inflammatory joint disease.


   There are several classifications of deformity severity in DDH: Crowe and Hartofilakidis25 are widely used classification systems and are composite for both sides of the hip. The Edinburgh system17 uses similar criteria but divides the problems into femur and acetabulum to allow a detailed plan for each bone to be formulated (Table 1).



PATHOGENESIS


   Specific conditions and their treatment cause specific deformities and ultimately specific patterns of secondary OA and symptomatology.


   Congenital and acquired causes of deformity around the hip joint are listed in Table 2.



   Osteotomies performed as realignment or conservative joint-sparing procedures to treat these conditions create new iatrogenic deformities and technical difficulties when hip reconstruction is considered:


   Perthes—valgising proximal femoral osteotomy +/− trochanteric advancement

   DDH—varising proximal femoral osteotomy, +/− derotation, +/− extension

   Slipped capital femoral epiphysis (SCFE)—valgising proximal femoral osteotomy, +/− derotation, +/− flexion

   Coxa vara—valgising proximal femoral osteotomy, +/− derotation

   Retained metalwork may be overgrown, broken, or obsolete. Careful planning is required to decide whether metalwork should be removed or retained and consideration given to the consequences of its removal.


   Deformity of the acetabulum and proximal femur disrupts hip kinematics and generates pain via the following:


   Increased joint reaction force—secondary to abductor dysfunction and coupled with reduced joint contact area leads to high load per unit area and early failure with secondary OA.

   Impingement of the following:



   Large, abnormal nonconcentric femoral head on the acetabulum (FIG 1)




   Overgrown greater trochanter (GT) on the ilium during hinged abduction



   Highly dislocated femoral head with the false acetabulum or ilium

   Leg length discrepancy (LLD) and altered gait kinematics, causing abnormal loading of the lumbar spine and lower limbs.

   Lower limb mechanical axis disruption with overloading and subsequent OA of the knee and lumbar spine

   Deformities at different levels create different problems as outlined in Table 3.



NATURAL HISTORY


   Patients with deformity develop OA at an earlier age than those without deformity. The mean age at the time THA is performed in patients with deformity is 45 to 50 years old.7,20,23


PATIENT HISTORY AND PHYSICAL FINDINGS


   Patients with degenerative joint disease resulting from deformity around the hip present with exertional groin pain, knee pain (either referred or secondary long-leg arthritis), or lower back pain in addition to what may be a long-standing deformity, with or without LLD.


   Symptoms may have been present chronically with recent progression of functional limitations.


   Patients with underlying DDH may present with iliopsoas tendon snapping over an anteverted, uncovered, sometimes large, femoral head or secondary acetabular osteophyte (see FIG 1).


   Patients with congenital deformities may have associated conditions which must be considered; for example, fixed scoliosis (congenital, idiopathic, or acquired) or complex medical problems.


   Short stature/dwarfism will affect implant sizes.


   LLD may not be obvious in bilateral disease.


   Following fracture with or without fixation, degenerative joint disease with pain, stiffness, and functional limitation may have developed rapidly following the acute development of deformity and mechanical malalignment.


   Examination must include the following:


   Observation of gait and Trendelenburg test with Medical Research Council (MRC) Scale for Muscle Strength grading of hip abductor power

   Observation of surgical scars to indicate previous hip approaches

   Hip range of motion—increased internal rotation and decreased external rotation is indicative of excessive femoral anteversion prior to the stiffness of advanced OA.

   Anterior impingement test

   Accurate documentation of true and apparent leg lengths

   Neurologic assessment and documentation of lower limb vascular status

   Examination of ipsilateral knee, lumbar spine, and contralateral hip

   Examination of the spine and sitting posture to determine if any spinal curvature secondary to leg length problems is correctable. This is important in older patients in whom correcting an LLD may create an unstable spinal deformity.

IMAGING AND OTHER DIAGNOSTIC STUDIES


   Sufficient imaging should be performed to gain an understanding of the three-dimensional (3-D) anatomy of the deformity and facilitate planning of its correction and the implantation of THA components.


   In many cases for the experienced surgeon, this requires plain radiographs only:


   Weight-bearing anteroposterior (AP) pelvis plus lateral of hip

   Full-length femur AP and lateral to assess femoral deformity and anterior femoral bow

   Judet views to assess anterior and posterior columns in acetabular deformity

   Standing hip-knee-ankle x-rays to assess leg lengths and knee joint level. Some patients who have undergone surgery around the hip in childhood may experience overgrowth distally.

   Computed tomography (CT) scan with or without 3-D reconstruction (see FIG 1) enables visualization of multiplanar deformities in addition to assessment of acetabular bone stock, femoral canal diameter, GT position, and femoral neck version relative to the condylar axis of the knee (FIG 2). This allows detailed planning to be carried out.



DIFFERENTIAL DIAGNOSIS


   See Pathogenesis section.


NONOPERATIVE MANAGEMENT


   As for primary hip OA, nonoperative management consists of simple analgesia, weight loss, activity modification, physical therapy, and orthotics to address LLD.


SURGICAL MANAGEMENT


   Surgical management is indicated when conservative management has failed. The goals of surgical management are as follows:


   Restoration of hip kinetics and kinematics, including hip center, acetabular and femoral version, abductor length, and GT position

   Correction of lower limb mechanical alignment

   Reconstruction of femoral and acetabular integrity to provide prosthesis containment

   Joint stability

   Achieving these goals may require adding acetabular bone stock and correcting deformities with multiplanar osteotomies.


   Subtrochanteric osteotomy should be performed if


   Restoring the hip center will lengthen the limb by greater than 4 cm, producing sciatic nerve traction

   Significant angular/rotational/translational deformity prohibits stem access down the diaphysis or disrupts the mechanical axis of the lower limb.

   Removal of awkward metalwork under direct vision

   Use implants with which you are familiar for these difficult cases, make the hip look normal, and conduct the procedure as usual. Both cemented23 and cementless stems with diaphyseal engagement31 have been used successfully in deformity cases in combination with subtrochanteric osteotomy. Our practice is to use a cemented, collarless, polished tapered stem routinely or a cementless, modular, fluted tapered stem if required. Custom-made implants may be necessary in rare cases, particularly if the endosteal anatomy is abnormal.


   Cemented stems provide immediate stability in osteopenic bone with a narrow canal. They also provided proximal metaphyseal stability if osteotomy is required. Cemented stems do not depend on metaphyseal fit and fill to obtain stability, as proximally coated cementless stems do, and can be difficult in these cases.


   Modular cementless femoral reconstruction systems with metaphyseal sleeves and long stems can correct femoral version independently of metaphyseal fit and fill,3,41 but they do not alter the position of the GT relative to the distal femoral condyles and thus do not restore physiologic abductor orientation or the mechanical alignment of the lower limb unless coupled with a trochanteric or subtrochanteric osteotomy (FIG 3). The diaphyseal stem provides relative stability in comparison to an osteotomy, but rotational stability depends on the diaphyseal cortical engagement of polished flutes only, with no ongrowth/ingrowth potential. Metaphyseal capture following a subtrochanteric osteotomy can be difficult with an incidence of nonunion that can be reduced by plating the osteotomy.



   Short-stem cementless components require a long, intact neck for rotational support and good-quality metaphyseal bone stock.38 This is often absent in femoral deformity. These implants cannot correct for version or leg length and are not recommended when femoral deformity is present, although their short stem may seem attractive.


   Custom-made stems accommodate rather than correct deformity. They can be essential in very narrow femoral canals (see FIG 2) but are often also used in metaphyseal level deformity. When they are used to accommodate rather than correct metaphyseal level deformity, they do not restore mechanical alignment and are therefore exposed to high-bending moments with associated risks of aseptic loosening and cantilever bending. Failure to restore the mechanical axis of the lower limb can hasten ipsilateral knee OA development.


   Resurfacing does not correct deformity, particularly the often extreme femoral anteversion in DDH. In less severe cases, the acetabular version can be altered to accommodate excessive version of the femoral neck, but this must be planned if the acetabulum is inserted before the femoral head.


   Scarring from previous surgery can compromise ideal skin incision location and make exposure difficult with increased need for trochanteric osteotomy to obtain access to the diaphysis and difficulty reaming the femoral canal in up to 35% of cases.6,16


   Removal of retained metalwork adds to surgical time. Fresh screw holes act as stress risers and allow cement extrusion. They also act as stress risers for uncemented prosthesis, which rely on high initial hoop stresses. Although consideration should be given on removing metalwork as a separate earlier procedure, the implants are often overgrown with bone, and any defect created by removal rarely heals (FIG 4). Plate removal in particular can leave a gutter in the cortex, which is difficult to manage. Leaving the plate but removing the screws either in the usual manner or cutting endosteally under direct vision at the time of THA is recommended. Overdrilling leaves large defects in what is usually a small femur.



Approach Planning


   Previous surgery may determine skin incision.


   Trochanteric osteotomy (standard, extended, or subtrochanteric) may be required for access to the femur.


   Excessive anteversion and severe arthritis leading to stiffness or a megahead can lead to difficulties on dislocation of the hip (see FIG 1). A combined anterior and posterior approach should be used to release tight structures and identify bone anatomy before cutting bone.


Bone Quantity and Quality


   Acetabular defects may require bone stock restoration—is adequate autograft available or will trabecular metal or allograft be required?


   Medialization of the acetabulum is well reported with good results.18


   Cemented implants may be more appropriate in osteopenic bone.


Implant Type


   Templating is essential to decide whether standard, revision, or custom-made implants are necessary. A knowledge of the range of implants available is essential (eg, implants for the Asia Pacific market are often much smaller than for Western implants).


   Nonprimary implants have been required in up to 40% of femoral deformity cases31; however, this is not our experience with cemented prostheses.


Implant Size


   The acetabulum is often small anteroposteriorly and the femoral canal is narrow.


Acetabulum


   Measure acetabular diameter on preoperative radiographs.


   Ensure that small enough implants are available.


   This will also determine head size and may affect bearing selection.


   Use cemented for extremely small acetabula, and remove polyethylene from the anterior and posterior surface with a knife to fit.


Femur


   Measure canal diameter on preoperative radiographs/CT.


   Organize custom stems if endosteum is very narrow or abnormally shaped.


   Ensure that smaller stems are available to accommodate small, narrow femurs.


   Longer stems should be available if subtrochanteric osteotomy is planned, fracture/perforation is a significant risk, or screw holes will be present in removed metalwork.


   Long stems must be slim to accommodate narrow femurs but long enough to bypass the osteotomy site, screw holes, and fracture site by two cortical diameters.


   Usually, there is considerable anterior femoral bowing and stem entry, and length must be planned to avoid anterior perforation.


Other Hardware


   Retained metalwork


   Metalwork is often still in situ from previous realignment, joint-sparing procedures, or fracture fixation.

   Identify manufacturers and ensure that appropriate removal instrumentation is present.

   Ensure that metal cutting equipment is available.

   If plates are overgrown, consider retaining the plate but removing screws (see FIG 4).

   Consider subtrochanteric femoral osteotomy to remove retained screws under direct vision.

   Wiring systems


   Required for diaphyseal fracture prophylaxis if using cementless stem

   Need to be available due to the high rate of intraoperative fracture (particularly when using cementless stems)

   Osteotomy stabilization


   Plate and unicortical screws for subtrochanteric osteotomy stabilization

   Temporary double plating to allow insertion may be necessary

Heterotopic Ossification Prophylaxis


   Consider if previous heterotropic ossification (HO), previous fracture surgery, or if trochanteric osteotomy is planned.


Consent


   Consent is to discuss with the patient the increased risk of complications (leg length, neurovascular complication, implant loosening, and fracture) and patient expectations need to be managed accordingly.


Bilateral Deformity


   In many cases, bilateral deformity exists, especially in DDH. Performing one THA may worsen LLD, and plans to schedule the second THA should be made early (see FIG 4) or acceptance of a shoe raise agreed (FIG 5).



Positioning


   The patient is placed in the lateral position with a posterior lumbosacral support and an anterior support placed on to the anterior superior iliac spine to stabilize the pelvis.


Approach


   Skin incisions from previous surgery are used with scar excision where possible to improve cosmesis.


   A posterior approach maintains abductor integrity, provides a circumferential view of the acetabulum, and is extensile to facilitate femoral osteotomy. Performing trochanteric osteotomy may defunction abductors in these extreme cases (reattachment is difficult), and subtrochanteric osteotomy, although sometimes necessary prior to dislocation, creates multiple fragments which can be difficult to manage while preparing the acetabulum.


TECHNIQUES

   Exposure


   A posterior approach, with the option of a direct anterior through the same incision, gives a circumferential view of the true acetabulum, preserves the abductors facilitating the soft tissue tension method for judging resection length in femoral osteotomy, and is extensile.

   Combining the posterior and true anterior approaches allows accurate neck resection in situ (or debulking of the often anteriorly subluxed femoral head) under direct vision prior to dislocation. This is particularly important in the stiff, fixed, externally rotated hip, which cannot be accessed from the back alone (see FIG 1).

   Occasionally, the head can be almost subcutaneous and removal of the anterior acetabular osteophyte is necessary to avoid impingement in flexion.

   Iliopsoas release from lesser trochanter allows proximal femoral descent.

   Total capsulectomy allows the proximal femur to be brought distally for hip center restoration.

   The sciatic nerve is usually found running over the ischium and can be traced back to the sciatic notch. It need not be mobilized unless a previous pelvic osteotomy has caused scarring and adhesions.

   The femoral bundle is rarely identified even when a direct anterior approach is added.

   Acetabular Reconstruction—Identifying the True Acetabulum in Severe DDH


   Indication: DDH or proximal femoral focal deficiency (PFFD) is where the femoral head does not articulate with the true acetabulum (TECH FIG 1).


   The femoral head may be articulating with a false acetabulum or may even be trapped in the abductor musculature in high dislocations.

   In these circumstances, the true acetabulum is often small and triangular with a narrow entry. Overhanging osteophytes close down the entry, but the transverse ligament is a constant indicator of the true acetabulum location.

   Medial osteophyte must be removed to identify the true floor.

   Acetabular Reconstruction—Femoral Head Autograft


   Indication: Recreating an anatomic hip center when the resulting position is associated with anterosuperior roof deficiency of greater than 20%.

   The true acetabulum is prepared as for a standard cemented acetabular component (see TECH FIG 1). The final acetabular reamings are kept as graft for the procedure later.

   The superior segmental defect is delineated by inserting a trial cup (TECH FIG 2A,B). The defect is prepared using gouges to remove fibrocartilage. The femoral head is similarly prepared by removing fibrocartilage.



   A generous wedge of the resected femoral head, which came from the defect, is cut (TECH FIG 2C,D) and placed with its sclerotic convexity against the prepared concave defect with the reamings from the true acetabulum placed in the bed to improve contact. This is held temporarily with a K-wire (TECH FIG 2E) and fixed with two superiorly placed partially threaded cancellous screws.

   Any autograft overhanging the true acetabulum is then reamed away (TECH FIG 2F), leaving an acetabular bulk autograft supported by host bone and a contained socket into which a standard acetabular component can be cemented using third-generation cementing techniques (TECH FIG 2G,H).

   Femoral Reconstruction—Subtrochanteric Shortening Osteotomy


   Indication: When recreating an anatomic hip center, subtrochanteric shortening osteotomy will lengthen the lower limb by greater than 3 cm with risk of sciatic nerve palsy.

   Femoral length, angulation, and GT position can be addressed concurrently using this technique.

   It reduces the need for custom implants (although small sizes may be required) and restores lower limb mechanical alignment.

   Single-plane osteotomy is easier for correction of complex deformity than a stepped osteotomy and requires a shorter stem to bypass it by a minimum of two shaft diameters.

   Perform acetabular implantation first.

   Identify the level for osteotomy distal to the lesser trochanter.

   Create a transverse osteotomy perpendicular to the shaft (TECH FIG 3A).



   The proximal femoral fragment is prepared with serial rasps to accept the femoral component which best fits with the largest offset. A burr can be used in a retrograde manner at the osteotomy site to aid this.

   The proximal fragment with rasp and trial head in situ is reduced into the acetabulum (TECH FIG 3B).

   Longitudinal traction is applied to the distal fragment and the amount of overlap of proximal and distal fragments is noted and marked. This length is resected perpendicular to the diaphysis (TECH FIG 3C). The burr can then be used in an antegrade fashion on the distal fragment if needed to remove any sclerotic or stenotic bone under direct vision.

   The resultant bone ends are opposed, and any rotational correction is made to align the GT 15 degrees from orthogonal to the transepicondylar axis of the knee. This restores the anatomic alignment of the direction of pull of the abductors with the transepicondylar knee axis.

   The appropriate femoral trial is then inserted and passed across the osteotomy and the osteotomy compressed with fracture reduction forceps (TECH FIG 3D).

   A 5- or 6-hole, one-third tubular plate or dynamic compression plate (DCP) is applied posteriorly with a combination of unicortical and bicortical screws as the in situ femoral trial allows (TECH FIG 3E–G). If the osteotomy is unstable, a temporary 2-hole plate can be applied at right angles to stabilize the construct temporarily.

   The stem is then cemented using third-generation techniques while the assistant’s fingers wrap around the femur anteriorly at the osteotomy site to prevent cement extrusion and provide tension against the plate and thus anterior compression at the osteotomy (TECH FIG 3H,I).

   After curing, morselized autologous graft is packed around the osteotomy site and the plate is left in situ.

   Femoral Reconstruction—Subtrochanteric Osteotomy with Derotation and angulation


   Indication: Angular deformity of femur requiring correction in order to implant stem and correct mechanical axis

   It is similar to shortening osteotomy, except the osteotomy made in the distal fragment should be oblique to correct angulation (TECH FIG 4B).




   The distal part has longitudinal traction applied, and the GT proximally is placed in the transepicondylar plane as before (TECH FIG 4C). The obliquity of the required osteotomy is determined by the overlap of the proximal osteotomy with the distal fragment (TECH FIG 4D). This is marked and the bone is resected accordingly.

   The distal fragment is prepared as before and the osteotomy is stabilized with a plate as before (TECH FIG 4E–G).

 


 















  
PEARLS AND PITFALLS

   Bone is often osteopenic and soft in deformity—avoid overreaming the acetabulum, especially medially, and use prophylactic femoral cables if using cementless implants.

   THA stability depends on the relative relationship in space between the femoral and acetabular components, not only their absolute alignment. Attention should be paid to recreating this coupling not only on individual implant alignment.

   Femoral canals are often oval in shape and thus may be narrower than they appear on a single-plane radiograph. Obtain CT scans to measure this and ensure that narrow enough stems are available. Bear in mind that derotation osteotomy will change the orientation of an ovoid canal and custom-made implants may be necessary.

   All-polyethylene cups and cement allow on-table AP diameter customization if required by removing polyethylene from the outside of the cup with a knife. This is not possible with cementless metal-backed systems.

   Manage patient expectations particularly regarding LLD and outcome, which may take 2 years to plateau.

POSTOPERATIVE CARE


   Where structural autograft or femoral osteotomy has been used, patients should be partial weight bearing for 6 weeks with standard posterior approach dislocation precautions.


OUTCOMES


   In addition to being technically difficult cases, patients with deformity are young and active and often have multiple operations. As such, THA performed for severe deformity is associated with more complications and worse survivorship when compared to standard primary THA.


   Arthroplasty register data have suggested that after adjusting for age, there is no significant difference in revision risk for THA performed for sequelae of pediatric hip disease compared to THA performed for OA, with a 10-year survival rate of 93.6% compared to 93.8%.14 However, more revisions were performed within 6 months in the pediatric hip disease group, with significantly more revisions for dislocation.14 These data do not consider the severity of deformity, which individual series have shown to be a key determinant of outcome.


   In DDH, mild deformity (eg, dysplasia without dislocation) rarely requires special techniques for deformity correction and is associated with THA survival comparable to that without deformity, with a 90% 15-year survival rate.19 Worse deformity with dislocation (low or high) is associated with higher rates of failure and the 15-year survival rate reduces to 75%.21


   Using the technique of structural roof allograft to treat severe acetabular dysplasia, 10-year survivorship for aseptic loosening is reported as 80% to 100% when combined with cemented cups5,23,32,40 and 91% to 100% with cementless.22,26,39 Longer term, 12- to 15-year survival of 65% to 96% is reported with cemented cups.1,13,24,29,37


   When a subtrochanteric osteotomy is used, studies with mean follow-up of greater than 5 years have shown femoral stem survival of 90% to 100% when a cementless stem is used8,15,30,33,35 and 80% to 91% with a cemented stem.9,23,30 Osteotomy union of 93% to 100% is reported with cementless stems8,15,30,33,35 and 90% to 97% with cemented stems.23,30


   Registry data have confirmed that there is no difference in the revision rate of short, cemented, collarless tapered stems (n = 1898; 7-year survival rate of 96.6%) compared to that of standard length stems (n = 39,956; 7-year survival of 96.5%) despite their use in a greater proportion of difficult DDH cases.10 Concerns regarding the biomechanical strength and stability of these slighter stems have not been confirmed, with no documented cases of stem fracture and no increase in aseptic loosening.


   Using a variety of cementless stems in the management of proximal femoral deformity, Mortazavi et al31 reported a mechanical failure rate (loose or revised) of 9% at 4 years. Twenty-one out of 58 (36%) required an osteotomy for exposure or deformity correction.


   Failure to restore the true hip center by positioning the acetabular component proximally and laterally increases the joint reaction force4 and shearing forces on the cup25 and does not restore the abductor moment arm. Cups placed 15 mm superiorly have significantly higher rates of aseptic loosening and revision of both acetabular and femoral components when compared to implants where the center of rotation has been anatomically restored.36


   Data on custom-made implants are difficult to interpret and long-term data are lacking. Medium-term follow-up of 48 cementless custom stems showed a survival rate of 96% at 4 years with failures due to early aseptic loosening.27 Follow-up of 70 different custom-made cementless stems reports a 99% (95% confidence interval, 90 to 100) 12-year survival rate with no femoral loosening up to 16 years.


   Previous proximal femoral osteotomy adversely affects THA outcomes with an intraoperative complication rate of 11% to 23%,6,16 increased risk of infection and septic THA failure rate of 8% at 5 to 10 years,14 and an overall failure rate of 21% at 10 years in 215 patients.16


COMPLICATIONS


   Compared to THA for primary OA, there is a greater risk of complications when THA is performed in the presence of deformity:


   The intraoperative fracture or femoral perforation rate is 5% to 22%.

   The dislocation rate is 6% to 7%.23,28

   The osteotomy nonunion rate is 3% to 7%.9,23,28

   The nerve palsy rate is 1% to 5%.3,6,16,23,27,36

   Residual LLD may still be present.34

REFERENCES


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Jul 31, 2016 | Posted by in Reconstructive surgery | Comments Off on Hip Arthroplasty in Severe Deformity

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