Fixed drug reaction

QUESTION 73

A 47-year-old African American woman presents to the dermatology clinic for the evaluation of a recurrent rash on the right leg. She states that the rash began 3 months ago, shortly after she was treated with amoxicillin–clavulanate for a bacterial sinus infection. The rash seemed to improve after the infection resolved but since then, the rash has recurred at least once every 2–3 weeks. She believes that the rash returns in almost the exact spots on the body and does not seem to spread. On examination, there are two distinct, well-defined round violaceous plaques with a border of erythema on the right upper leg (73). She is otherwise healthy but does report occasional ibuprofen use for minor joint pain.

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