Although fat grafting had a “bad reputation” in the past, it has become one of the most commonly performed procedures in both aesthetic and reconstructive plastic surgery. It started as autologous filler for facial rejuvenation, but now it has been used not only for facial rejuvenation but also for breast surgery, body contouring surgery, and other aspects of aesthetic and reconstructive surgery. Until recently, fat grafting has showed its regenerative potential and has been used to treat some of the difficult clinical problems facing plastic surgeons. As we know more about fat grafting, its mechanisms of how fat grafts survive, and their regenerative features, fat grafting as a relatively noninvasive procedure can gradually replace many of the aesthetic and reconstructive procedures in the future. It becomes a major armamentarium for plastic surgeons to rejuvenate aged tissues, to reconstruct a missing part of tissues, to reverse the disease process, and to treat certain pathologic conditions.
Since fat grafting has become a rapidly growing field in plastic surgery with much new advancement for aesthetic and reconstructive surgery, several visionary leaders, including the 3 editors of the issue, have formed a brand new international society, named International Society of Plastic and Regenerative Surgery (ISPRES), in 2011. This young, dynamic international society has gathered many talented plastic surgeons with primary interests and expertise in fat grafting. These 2 issues of Clinics in Plastic Surgery are representation of members of this young international organization and their excellent work being presented during the previous world congresses in Rome, Italy, Berlin, Germany, and Miami, USA. Part I of this special issue starts with the history and evolution of fat grafting, followed by the discovery and development of adipose tissue and adipose-derived stem cells. The biology, safety, regulation, and regenerative potential of adipose-derived stem cells are well summarized in this issue. This is followed by the best explanation on how fat grafts survive and remodel and the techniques on how to concentrate stem cells for fat grafting. The good summary on standardizing techniques for fat grafting as well as the update on cryopreservation of fat grafts is also presented in this issue. Clinical application of fat grafting for facial rejuvenation, gluteal augmentation, and treatment of burn and burn scars is presented in this issue as well.
We sincerely hope that you will enjoy reading this special issue of Clinics in Plastic Surgery . It represents a true team effort from worldwide experts of the ISPRES. We would like to express our heartfelt gratitude to all of the contributors for their expertise, dedication, and responsibility to produce such a world-class monograph of plastic surgery. It is certainly our privilege to work with these respected authors in this exciting field of plastic surgery. We would also like to express our appreciation to the publication team of Elsevier, who has put this remarkable issue together with the highest possible standard.