Many studies have been undertaken to determine the factors that affect surgical and postsurgical bleeding, and some techniques have been introduced to reduce the morbidity of bleeding such as suture techniques [7], local vasoconstricting agents [8–14] and hypotensive anesthesia on bleeding reduction have been reported by many authors [15, 16]. Sex hormone variations may also influence the hemostatic function in female adolescents [17–19]. Some studies showed that contraceptive medications may affect the hemostatic potential in women [20–22]. Sex hormone variations were also thought to be related to the hypercoagulable status during pregnancy [23, 24]. However, there are contradictive results about hemostatic status during the different phases of the menstrual cycle [18]. Some authors found that the levels of von Willebrand factor (VWF) and factor VIII were lowest during menstruation [25–28]. Some other studies reported that there were no cyclic variations in VWF, factor VIII, and factor XI during menstrual cycle [26, 29–32]. Several studies reported on the variations of fibrinogen levels during the menstrual cycle. Some of them reported the lowest levels of fibrinogen during the follicular or midfollicular or luteal phase, while other authors reported no cyclic variation [26, 29–31, 33–39].

High levels of estrogen are believed to be responsible for the proliferation of blood vessels and congestion within in the muscles of the abdominal wall and abdominal skin [40]. Since the estrogen levels change during the menstrual cycle, an influence on bleeding could be expected. It has been shown that the menstrual cycle causes periodic changes in female tissues such as the vagina, breast, oronasal mucosa, conjunctiva, and eustachian tube, which are more sensitive to hormonal changes [41–50].

Ali and Essam [51] reported abdominoplasty combined with Cesarean delivery carries a higher incidence of complications in a study that included 50 pregnant women. They did not report any complication regarding bleeding in their study groups, but they needed to exclude two of the patients from the study and halted the abdominoplasty procedure due to intrapartum uterine atony and bleeding.

Sariguney et al. [1] claimed that blood loss during the perimenstrual period is greater for breast reduction surgeries. Findikcioglu et al. [2] showed that the periovulatory period was detected as the phase in which most bleeding occurs for rhinoplasty patients. However, Findikcioglu et al. also showed that the menstrual period (even menopause) has no effect on intraoperative and postoperative blood loss for operations on sites that are less sensitive to sex hormone levels such as the abdomen, and that is the only study regarding the impact of the menstrual cycle on intraoperative and postoperative bleeding in abdominoplasty patients. Therefore, the results of this study suggest that considering the patient’s menstrual date is not of vital importance regarding perioperative blood loss when planning surgery for areas that are not directly affected by menstrual hormonal changes. Patients can also be informed that it is not necessary to postpone the operation during menstruation in the case of such surgeries.