In this report, we describe several cases of AE, which were observed around the patients’ time of puberty. In 1952, Peeper reported the case of a 46-year-old woman, who had a mild form of AE; and her main symptom was diarrhea with mucoid stools. The patient’s parents were third cousins and one of their siblings was reported to have had the symptoms of this disorder. Next, the case of a 23-year-old woman was described whose symptoms started when she was eight years old and her symptoms would only improve during her period of pregnancy [1].