• History: Not present at birth, grows rapidly over first couple of months

• Bright red nodule (see Fig. 20.1A)

• Lobules of small capillaries (GLUT-1-positive)

• Often extends into the subcutaneous

• History: Present at birth

• Site: Predilection for pressure points

• Oval shape

• Blue–red nodule with white–green halo (Fig. 20.2)

• Lobules of small capillaries (GLUT-1-negative)

• Mottled to solid red patches and red papules (Fig. 20.3A,B)

• Small lobules (tufts) of small capillaries

• Dilated lymphatic spaces

• May be autosomal dominant inheritance, particularly if multiple lesions

• Clustered blue papules (Fig. 20.3C,D)

• Dilated spaces lined by one to two layers of monomorphous cells with round blue nuclei

• Site: Often on the head/neck or trunk

• Firm or rubbery nodule or infiltrative plaque

• Skin-colored to red–purple

• May be multiple (see Fig. 20.4)

• Biphasic with increased vascularity and spindle cells (myofibroblasts)

• Site: Typically on the 2nd toe

• Firm, pink nodule (Fig. 20.5)

• Elongated spindle cells with cytoplasmic pink inclusions

• History: Intermittent blistering

• Brown–pink to red papulonodule

• Leathery surface (Fig. 20.6)

• Fried-egg-shaped cells with granular cytoplasm

• Bluish tinge

• Firm to hard plate-like papulonodule

• Lesion will “teeter-totter” with pressure on one side or another

• Shadow cells within butterscotch-colored keratin

• Site: Eyelid

• Bluish, translucent papule

• Cuboidal cells lining a lumen

• Site: Eyelids

• Flesh-colored papules

• Tadpole-shaped epithelium with clear cells and ductal differentiation

• Site: Face

• Yellow papule with central dell

• Dilated follicular infundibulum surrounded by sebaceous glands

• Bright red papule

• Clusters of dilated spaces lined by endothelial cells

• Site: Predilection for head/neck, fingers

• History of rapid growth

• Eroded red papule, often pedunculated