Vesicles and Papulopustules in Infants


Fig. 15.1 Neonatal cephalic pustulosis. Courtesy, Julie V Schaffer, MD. From Bolognia JL, Schaffer JV, Duncan KO, Ko CJ. Dermatology Essentials, 1e. Philadelphia: Saunders, 2014, with permission.


Absent comedones



Benign Cephalic Histiocytosis (Fig. 15.2)


Typically on the face or neck


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Fig. 15.2 Benign cephalic histiocytosis. A, Courtesy, Yale Dermatology Residents’ Slide Collection. A, From Bolognia JL, Schaffer JV, Duncan KO, Ko CJ. Dermatology Essentials, 1e. Philadelphia: Saunders, 2014, with permission.

Small (<5 mm) brown–red papules


Spontaneous resolution over time (months to years)






Histopathology:


Histiocytes (CD1a-negative) within the dermis



Eosinophilic Folliculitis


(see Chapter 9)




Body Folds


Langerhans Cell Histiocytosis (Fig. 15.3)


Favors the scalp and body folds


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Fig. 15.3 Langerhans cell histiocytosis. A, Courtesy, Irwin Braverman, MD; B, Courtesy, Jonathan Leventhal, MD.

Pink to red–brown papules, often with petechiae, sometimes eroded/ulcerated






Histopathology:


Histiocytes with reniform (kidney-shaped) nuclei that are langerin-, CD1a-, S100-positive



Acral


Acropustulosis of Infancy (Fig. 15.4)


Cyclical, typical age is 3 to 6 months up to 2–3 years of age


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Fig. 15.4 Acropustulosis of infancy. A, Courtesy, Deborah S Goddard, MD, Amy E Gilliam, MD, and Ilona J Frieden, MD. A, From Bolognia JL, Schaffer JV, Duncan KO, Ko CJ. Dermatology Essentials, 1e. Philadelphia: Saunders, 2014, with permission.

Pruritic vesicles






Histopathology:


Intraepidermal pustules



Scabies (Fig. 15.5, See Fig. 7.16A,B)


Can present like acropustulosis of infancy


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Fig. 15.5 Scabies. A, Courtesy, Yale Dermatology Residents’ Slide Collection.

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Mar 5, 2017 | Posted by in Dermatology | Comments Off on Vesicles and Papulopustules in Infants

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