Judicious use of TC on face depends on a number of factors such as indication, potency of the drug, age of the patient and duration, amount and frequency of application [12]. TCs have various therapeutic effects on the skin and hence are useful in hyperproliferative, inflammatory and immunologic disorders [11]. However, application of TC in diseases which are not steroid responsive or where TCs are contraindicated may lead to the catastrophic effects enumerated later [13]. The penetrability of the skin of the face is much higher than the skin of the other parts of the body because of its inherent thinness. Hence, TCs of higher potency should be avoided, and TCs of least potency should be applied on the skin of the face [12]. The age of the patient also determines the thickness of the skin of the face, e.g. children have even thinner skin than adults. Hence, TCs should preferably be avoided in this age group, and only TCs of least potency should be used if absolutely necessary [14, 15]. The duration of application is also important. It has been recommended that irrespective of the potency, TCs beyond a period of 2 weeks on the face should not be applied [11]. In fact most experts recommend once daily application of the proper amount of TC based on FTU [16] (Tables 13.1, 13.2, 13.3, 13.4 and 13.5).