Fig. 23.1
Advertising for bleaching creams (Courtesy of Pr. M. Diallo (Senegal))
The complications vary according with the degree of potency of the topical corticosteroids, the location of their application, and the duration and the frequency of applications.
Adverse effects are classified into local and systemic effects.
23.1 Local Adverse Effects
- A.
Skin infections:
- 1.
Mycoses:
Especially tinea faciei which is an uncommon dermatophytosis affecting the glabrous skin of the face that is frequently misdiagnosed, especially the forms whose appearance has been modified by inappropriate treatment usually by a topical steroid leading to the so-called tinea incognita where the diagnosis is often difficult (Fig. 23.2). One specific form known as tinea pseudoimbricata starts with central erythematous, scaly, pruritic plaques from which one to three centrifugally spreading, concentric circles emerge (Fig. 23.3). The clinical manifestation is called tinea pseudoimbricata because of its resemblance to the infection typically caused by Trichophyton concentricum [1, 2].
Fig. 23.2
Tinea incognita
Fig. 23.3
Tinea pseudoimbricata
Fig. 23.4
Profuse tinea
Fig. 23.5
Profuse tinea
- 2.
- 3.
Bacterial:
Acneiform eruptions are the most frequent complications of abuse of TCS. These include the following:
Perioral dermatitis which is an erythematous-papular and sometimes papular-pustular disease localized in the perioral region (Fig. 23.7). Regardless of the variation of the etiologic factors of this disease, it is thought that the long-term use of TCS is considered a major factor in the pathogenesis of the disease or at least a trigger factor.
Rosacea is a disease of the face that manifests with erythema, papulo-pustules and telangiectasias. Among the different factors cited in the pathogenesis of rosacea, a prolonged use of topical and even systemic corticosteroids is one of them (Fig. 23.8).
Acne is one of the most frequent skin conditions especially in young persons. Clinically it is characterized by a polymorphic pattern: open and closed comedones, papules, pustules, and even nodules. When the clinical picture turns to a monomorphous one (papules and pustules) especially when it is located on the back and chest, we should suspect a drug-induced acne and check for a misuse of topical corticosteroids (Fig. 23.9) [4, 5].
Fig. 23.7
Perioral dermatitis (Courtesy of Pr. A. Prohic – Bosnia)
Fig. 23.8
Rosacea
Fig. 23.9
Acne (courtesy of Pr. M. Diallo – Senegal)
Fig. 23.10
Erysipelas (Courtesy of Pr. M. Diallo-Senegal)
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- 1.