Treatment: These keratoses require no therapy. If they become inflamed or irritated, a simple shave biopsy removal is curative. Cryotherapy and curettage are often used to treat these benign skin growths, and both are extremely effective. After cryotherapy treatment, a blister usually forms at the base of the seborrheic keratosis, and within a day or two the keratosis falls off. Another extremely effective method of removal that can be done in the office is cryotherapy followed by a light curettage; this also allows for histological evaluation. Occasionally, dark brown or black seborrheic keratoses can mimic melanoma, and in other cases a melanoma may arise adjacent to a seborrheic keratosis and mislead the clinician. If there is ever a doubt that the growth could be a melanoma, a biopsy is required. This allows for pathological confirmation of the diagnosis.
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