5 Non-permanent fillers
Belotero®/Esthélis® and Teosyal®
Summary and Key Features
• Belotero®, Esthelis®, and Teosyal® are three hyaluronic acid families produced in Switzerland
• Good clinical data are available only for Belotero® Basic and Teosyal® Deep Lines
• At 6 months Belotero® Basic and Teosyal® Deep Lines still show at least a one-grade difference after treatment of the nasolabial folds
• Belotero® Basic and Teosyal® Deep Lines have a good safety profile
Hyaluronic acid dermal fillers
How to differentiate the different HA fillers? There are certain possibilities:
Those with good clinical data and those without
Those for more superficial and those for deeper injections
Those with a few products and those with product families
Those easy to inject and those more difficult to inject
Belotero®
Belotero® is produced by the Swiss company Anteis SA and distributed by Merz Pharmaceuticals. The stabilizer is BDDE and according to the manufacturer two cross-linking processes are used leading to a cohesive and polydensified matrix, which is supposed to ease injection while maintaining long-lasting results. Belotero® offers three different formulations: Belotero® Soft, Belotero® Basic and Belotero® Intense (Table 5.1, Figs 5.1 and 5.2).