Patients with type II disease should have screening MRI studies of the brain and the rest of the central nervous system to look for schwannomas. Type II disease, because of the presence of bilateral schwannomas, is a much more serious and life-altering disease than type I. The follow-up management of type II neurofibromatosis requires a multidisciplinary approach. Ophthalmology, otolaryngology, neurosurgery, and internal medicine physicians need to coordinate care for these patients. Neurosurgery and localized radiotherapy have been used to treat the brain tumors.