New therapies are being investigated to treat hyperhidrosis. Novel methods of delivering botulinum toxins and new topical therapies have been developed. Devices that can deliver heat to the area of the eccrine units can reduce sweating. Further studies need to be performed.
Key points
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Topical botulinum toxin A can be delivered through intact skin.
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Topical anticholinergic agents may provide efficacy with decreased adverse effects.
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Devices delivering energy such as lasers, ultrasound, and radiofrequency may reduce focal sweat.
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Limited data are available, and more research is needed.