Management of Nutritional Complications


Type of complication

Key nutrient(s)

Clinical findings

Supplementation

Metabolic bone disease

Vitamin D

Deficiency: rickets, osteomalacia

Oral (prevention): calcium 1,500 mg/day (band), 1,500–2,000 mg/day (gastric bypass), 1,800–2,400 mg/day (DS)

Calcium (magnesium, phosphorus, vitamin K)

Toxicity: hypercalcemia, anorexia, nausea, abdominal pain, lethargy, weight loss, polyuria, constipation, confusion, coma; cardiac and renal damage

Oral (treatment): vitamin D3 2,000 IU/day

Oral (treatment/severe deficiency): vitamin D2 50–150,000 IU/day

Neurologic

Thiamin (vitamin B 1)

Deficiency (thiamin): poor appetite, confusion, weakness, anorexia, tachycardia, muscle cramps, paresthesia, symmetric motor and sensory neuropathy

Oral (treatment): thiamin 10–100 mgs 1–3×/day

Vitamin B12

Deficiency (B12): glossitis, weakness, pallor, depression, peripheral neuropathy, paresthesia, dementia

IV (treatment): thiamin 100–500 mgs/day 1–3×/day

Copper

Deficiency (copper): leukopenia, anemia, hypopigmentation of hair

Oral/sublingual: vitamin B12 250–350 μ(mu)g 1–2×/day or 1,000 μg/month

Toxicity (copper): anemia, nausea, vomiting, muscle aches, abdominal pain

Intranasal: vitamin B12 500 μ(mu)g/week

IM: vitamin B12 1,000 μ(mu)g/month or 1,000–3,000 μ(mu)g every 6–12 months

Nutritional anemia

Iron

Deficiency (iron): fatigue, irritability, tachycardia, palpitations, cheilosis, koilonychia, pica

Oral (treatment): ferrous sulfate, fumarate, or gluconate, 320 mg (with vitamin C) 2×/day between meals

Vitamin B12

Toxicity (iron): nausea, abdominal pain, vomiting; renal, cardiac and hepatic damage (severe)

Parenteral: (treatment/severe deficiency) iron dextran, ferric gluconate, or ferric sucrose

Folic acid (copper, vitamin A, selenium)

Deficiency (B12): glossitis, weakness, pallor, depression, peripheral neuropathy, paresthesia, dementia

Oral/sublingual: vitamin B12 250–350 μ(mu)g 1–2×/day or 1,000 μ(mu)g/month

Deficiency (folic acid): glossitis, weakness, diarrhea, fatigue, depression, confusion, irritability, neural tube defects during pregnancy

Intranasal: vitamin B12 500 μ(mu)g/week

IM: vitamin B12 1,000 μ(mu)g/month or 1,000–3,000 μ(mu)g every 6–12 months

Oral (prevention): folate 400–800 mcg/day

Oral (treatment): copper 6 mg (elemental)/day × 1 week, then 4 mg/day the next week, and 2 mg daily thereafter

Ocular

Vitamin A

Deficiency: night blindness, xerosis and hyperkeratinization of the skin, Bitot’s spots (early), keratomalacia, blindness (late), loss of taste, fatigue, poor bone growth, weak tooth enamel

Oral: vitamin A 5,000–10,000 IU/day until serum levels normalize; up to 65,000 IU/day for 2–3 months for resolution of symptoms

Beta carotene, retinol

Toxicity: gingivitis, cheilitis, erythema, desquamation, dry skin, bone fractures, blurred vision, hair loss; pseudotumor cerebri and hepatic failure (severe) (beta carotene form rarely associated w/ toxicity)

Parenteral: (treatment/severe deficiency) vitamin A 25,000 IU/day

Protein malnutrition

Protein

Deficiency: fatigue, weakness, hair loss, edema, temporal wasting

Oral: high-quality liquid protein formula; feeding tube or parenteral (treatment/severe deficiency)



It is worth mentioning that patients that have mechanical or metabolic complications that result in intractable vomiting might develop over time food aversion that by itself perpetuates emesis. Psychological or psychiatric intervention to rule out this disorder is imperative after all other potential causes have been ruled out.




Conclusion



Supplement Noncompliance


Poor clinical follow-up often equates to poor compliance with routine blood work and micronutrient supplements. Forgetfulness, poor education about the need for lifelong supplementation, or ironically deficiency states themselves (such as memory loss from vitamin B12 deficiency) may contribute. Patients may believe that being at a healthy weight, and/or eating larger portions of food, months and years after surgery, translates to not needing to take supplements. Alternatively, they may believe that regaining weight after surgery means additional vitamins and minerals are no longer needed. Many are knowledgeable regarding the importance of supplementation, but find the frequency of taking pills hard to sustain, have difficulty swallowing (sometimes large) pills, or have run into financial difficulties and no longer purchase supplements. Methods of managing these patients and increasing compliance include routinely reaching out via email, telephone, or postcards to remind them of annual visits, blood work that is due, support group meeting schedules, and publications from your practice or third-party organizations. It is helpful to reinforce to patients that long-term follow-up with your office and attending support groups are predictive of their success [15, 17]. Another way to increase compliance is to educate patients on alternative ways to take supplements. Some patients prefer crushing or dissolving pills, selecting chewable, liquid, or powdered (or even injectable) forms, to swallowing them on a daily basis, but some are unaware of these options.

Apr 2, 2016 | Posted by in General Surgery | Comments Off on Management of Nutritional Complications

Full access? Get Clinical Tree

Get Clinical Tree app for offline access