David M. Pariser, MD, FACP, FAAD, Editor

It is most commonly a chronic idiopathic (primary) condition; however, secondary medical conditions or medications should be excluded. Idiopathic hyperhidrosis localized to certain areas of the body is called primary focal hyperhidrosis. Primary focal hyperhidrosis usually affects the axillae, palms, and soles, but other areas such as face and scalp, inframammary area, and groin may also be affected.

This issue is devoted to the diagnosis and treatment of primary focal hyperhidrosis with emphasis on how the disorder affects quality of life. All current treatments are reviewed with an eye to the practical nature of these modalities for the practicing clinician.

After an introduction regarding the incidence, prevalence, and impact on quality of life, there are articles on topical therapies, iontophoresis, and botulinum toxin with attention not only to axillary disease but also other body areas where it may be used effectively as well. Systemic as well as procedural therapies and surgery as well as emerging and investigational treatments are also discussed. Finally, the practical aspects of incorporating diagnosis and treatment of hyperhidrosis into clinical practice and resources for patients and physicians conclude the issue.

On behalf of the international group of authors, all known for their expertise in hyperhidrosis, I hope that the information presented in this issue will heighten your awareness of this socially disabling problem and that you will appreciate that diagnosis and treatment of patients with primary focal hyperhidrosis is easily learned, leads to a great improvement of patients’ quality of life, can be easily integrated into routine office practice, and is economically viable for a busy outpatient practice.