Histology: A lone cystic space is seen within the dermis. The cyst is well circumscribed, and the lining of the cyst contains two layers of cells. The cells are cuboidal and have an eosinophilic cytoplasm. The cell wall has no myoepithelial cell component. The cysts are found near eccrine gland structures. There is minimal to no inflammatory infiltrate surrounding the cyst. The central cavity of the cyst contains an small amount of lightly eosinophilic material that is consistent with eccrine gland secretions. There is no evidence for sebaceous gland or apocrine gland secretion or derivation.
Treatment: Most eccrine hidrocystomas are biopsied to make sure they are not actually basal cell carcinomas. They rarely recur after biopsy. If they do recur, no treatment is required. Surgical excision is the definitive treatment and is curative. Hidrocystomas almost never recur after excision.
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