Treatment: Therapy is often aimed at reducing inflammation and bacterial superinfection. There is no curative therapy, and most treatments have only anecdotal reports of success. Topical clindamycin and other antibacterial products such as benzyl peroxide are often the first-line agents employed for mild disease. Oral antibiotics, typically in the tetracycline class, are often used because they have both antiinflammatory and antibacterial properties. Weight loss must be advocated. Other agents that have had limited success include isotretinoin, etanercept, and infliximab. Surgical options include wide local excisions to remove the affected tissue and repair with complex flap closure. Liposuction has also been tried in an attempt to remove the affected apocrine gland hair follicle unit. The only potential for cure is with a surgical approach. This approach seems to work best for axillary disease; groin and inframammary disease almost always recurs after surgery. It is also of the utmost importance to address patients’ psychosocial needs, because this disease has a devastating toll on the patients it afflicts.
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