Granulomatous disorders represent a unique group of diseases, both noninfectious and infectious, that require the utmost clinical pathologic correlation combined with a keen sense of inquiry for underlying systemic disease and immunosuppression. Dermatologists (and others, such as rheumatologists, oncologists, endocrinologists, pulmonologists, oral maxillary surgeons, and infectious disease specialists) need to be able to differentiate these entities, evaluate patients for specific underlying systemic disease (ie, from diabetes to cancer), and treat them with a wide range of immunosuppressant to anti-infectious medications. This issue supplies the readers with a comprehensive, up-to-date, and evidence-based review of multiple granulomatous disorders (ie, palisading, epithelioid, xanthomatous, vasculitic, lymphoproliferative, drug-induced, foreign body reaction, caseating, and suppurative).
This collection of reviews comes from the hard work and passion of hand-selected experts in the realm of granulomatous disorders throughout the world. They have been tasked to provide the reader with the most current information on the etiopathogenesis, clinical/systemic manifestations, and therapeutic modalities of granulomatous disorders. I know you will be pleased with the quality of research, writing, and digital images as much as I am. As most dermatologists are visual learners, I have added a “bonus” supplemental atlas from my own digital image collection to give additional examples of the diseases discussed in this issue.