Some glomangiomas have been described to be inherited in an autosomal dominant fashion. These cases are caused by a deletion defect in the glomulin (GLMN) gene, which is located on the short arm of chromosome 1. The exact function of the protein encoded by this gene or how its defect causes glomangiomas is still not understood.
Treatment: Glomus tumors are successfully treated with complete surgical excision. Glomangiomas, because of their size, can be excised in a staged approach or with the help of tissue expanders. Reports of treatment with laser ablation, electrocauterization, and sclerotherapy, with some success, have been documented in the literature.