Treatment: The main point in therapy is making the correct diagnosis and removing the offending agent. Once this is done, the lesions heal within a month. Medium to potent topical corticosteroids can be used to help relieve pruritus and potentially speed healing. Fixed drug eruptions often leave an area of postinflammatory hyperpigmentation or hypopigmentation after the initial reaction has resolved. This pigmentary abnormality can last for months to years.