Treatment: Many medications can be used to treat the acroparesthesias, and they typically come from the antiseizure class of medications. Phenytoin and gabapentin are used to help control the frequency and duration of the episodes. In the past, there were no specific therapies for Fabry disease. End-stage renal disease often required kidney transplantation. Enzyme replacement therapy has been available since 2003 and has begun to have an impact on morbidity in these patients. Long-term studies are needed to make any conclusions regarding their effects on mortality.
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