Treatment: Small, isolated epidermal nevi can be removed with shave removal technique. They have a high rate of recurrence with this technique, but recurrence may take many years. The advantages of this technique are that it is relatively easy, noninvasive, and quick, and it provides an opportunity to histopathologically evaluate the tissue for any evidence of epidermolytic hyperkeratosis. The disadvantage of shave removal is that it is appropriate only for small epidermal nevi. Cryotherapy with liquid nitrogen has been used successfully, but it may leave unsightly hypopigmentation in darker-skinned individuals and should be used with caution.

Complete surgical excision is curative for small epidermal nevi. However, it leaves a scar that may be more noticeable than the nevus was. Laser resurfacing, dermabrasion, and chemical peels have been used to help smooth out the appearance of epidermal nevi.

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