Treatment: No good therapy exists for calciphylaxis. Aggressive supportive care and early treatment of superinfections are critical. Surgical debridement of wounds is necessary to remove necrotic tissue that provides a portal for infection. Renal transplantation offers some hope for cure. Treatment with sodium thiosulfate has shown success in some anecdotal reports, but this is not a universal cure. The newer bisphosphonate medications have also been used with limited success. Parathyroidectomy may help initially with the ulcerations, but it does not decrease mortality.
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