Narcotics (for pain control) and antivenin have been used to treat black widow spider bites and have been helpful. The antivenin is derived from horse serum, and there is a risk of an allergic reaction in susceptible patients. Brown recluse spider bites have been treated with many agents, including dapsone, to try to mitigate some of the inflammation-induced skin damage. Recognition of these spiders and avoidance is critical.
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