Medical therapy with imiquimod or 5-fluorouracil has also been shown to be useful in selected BCCs, usually the small, superficial type. One of the newest treatments is photodynamic therapy. It is performed by applying aminolevulinic acid to the skin tumor and then exposing the area to visible blue light. An oral inhibitor of the smoothened protein, called GDC-0449, has shown excellent results in patients with the nevoid BCC syndrome.