33 DISORDERS OF THE MOUTH

Disorders of the Mouth Image



Diseases of the Lips ICD-9: 528.5 ° ICD-10: K13.0







Angular Cheilitis (Perlèche) image


image Associated with increased moisture at commissures, salivation (at sleep).


image Predisposing factors: thumb sucking in children; sagging face and loss of teeth in older persons; candidiasis in immunocompromised persons; Staphylococcus aureus in atopic dermatitis and isotretinoin treatment.


image Findings: erythema and maceration at commissures (see Fig. 33-1); white candidal colony.


image Diagnosis: KOH for candidiasis; culture for S. aureus, Candida.


image Management: Identify and treat causes.






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Figure 33-1. Angular cheilitis Mild erythema and scaling in bilateral commissures. (Courtesy of Dr. Nathaniel Treister.)







Actinic Cheilitis image


Actinic/solar keratoses, usually of the lower lip. Rule out squamous cell carcinoma in situ (SCCIN) or invasive if papule or nodule or ulcer occurs. (See “Solar Keratosis” in Section 10.)






Conditions of the Tongue, Palate, and Mandible ICD-9: 528.6, 528.7, 529 ° ICD-10: K14







Fissured Tongue image


image Normal variant in up to 11% of population. Asymptomatic.


image Findings: Multiple folds with anterior-posterior orientation on the dorsal surface of the tongue (Figs. 33-2 and 33-3).


image Associated disorders: Psoriasis, Down syndrome, acromegaly, Sjögren syndrome.


image Synonyms: Lingua fissurata, lingua plicata, scrotal tongue, grooved tongue, furrowed tongue.






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Figure 33-2. Fissured tongue Deep furrows on the dorsum of the tongue are asymptomatic.


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Figure 33-3. Hairy tongue Defective desquamation of filiform papilla noted in posterior aspect of tongue. Tongue has a white surface due to retained keratin. (Courtesy of Dr. Nathaniel Treister.)







Black or White Hairy Tongue image


image Pathogenesis: Defective desquamation of filiform papillae resulting in hair-like projections on the dorsum of the tongue.


image Associations: Heavy tobacco use, mouth breathing, systemic antibiotic therapy, poor oral hygiene, general debilitation, radiation therapy, chronic use of bismuth-containing antacids, lack of dietary roughage.


image Symptoms: Gagging sensation, altered taste, halitosis, cosmetic disfigurement.


image Findings: Furry plaques on dorsal tongue (Fig. 33-3). Chromogenic bacteria or exogenous pigment stain tongue: white, yellow, green, brown, black. Candidiasis may occur secondarily.


image Management: Eliminate predisposing factors; good oral hygiene.


image Synonym: Lingua villosa (nigra).











Oral Hairy Leukoplakia (See Section 27) image


image Pathogenesis: Epstein–Barr virus infection; low CD4 cell counts.


image Findings: White corrugated plaques on lateral aspects of tongue (see Fig. 27-66). Does not occur in successfully treated HIV/AIDS.











Migratory Glossitis ICD-9: 529.1 ° ICD-10: K14.1 image


image Irregular areas of dekeratinized and desquamated filiform papillae (red in color) are surrounded by elevated whitish or yellow margins (Fig. 33-4).


image Etiology: unknown; possible link with psoriasis. Incidence: common; usually asymptomatic.


image Synonym: Geographic tongue.






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Figure 33-4. Migratory glossitis Areas of hyperkeratosis alternate with areas of normal pink epithelium, creating a geographic pattern in a female with psoriasis.







Palate and Mandibular Torus


image Pathogenesis: genetic predisposition, ? autosomal dominant in some series, more common in females, Native Americans, Eskimos (torus palatini); local stressors (mandibular and palatal tori), bony protrusions


image Associations: bruxism


image Symptoms: may be complicated by ulceration; usually asymptomatic


image Findings: palatal tori are usually in midline of palate and less than 2 cm, but can vary in size through life; mandibular tori found usually near premolars; rarely bilateral. They are smooth, nodular protrusions (Figure 34-5).


image Management: not needed; if create ulcerations or complicate dental prosthesis, surgery can be done. Have been used as autogenous bone grafts.






Diseases of the Gingiva, Periodontium, and Mucous Membranes ICD-9: 523 image ICD-10: K06







Gingivitis and Periodontitis image


image Gingivitis: Erythema, edema, blunting of interdental papillae without bone loss. Predisposing factors: poor oral hygiene, tobacco use, diabetes.


image Periodontitis: Chronic infection of connective tissue, periodontal ligament, and alveolar bone; most common cause of tooth loss in adults.


image Course: Accumulation of subgingival calculus (calcified plaque) and Actinobacillus actinomycetemcomitans infection results in painless soft tissue edema, insidious alveolar bone resorption, deepening periodontal pockets, and tooth loss.






Erosive Gingivostomatitis


Reaction pattern associated with viral infection, autoimmunity, lichen planus (LP), erythema multiforme, pemphigus, cicatricial pemphigoid. Findings: Erythema, desquamation, and edema of gingivae. Other mucocutaneous sites may be affected.



Lichenoid Mucositis


Findings: Reticulated white plaques and painful erosions on mucosal surfaces.


Etiology: LP, drugs (NSAIDs, antihypertensive agents), allergic contact dermatitis, graft-versus-host disease.


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Figure 33-5. (A) Torus palatinus Bony protrusion in the midline, upper palate. (B) Mandibular torus Unilateral protrusion near premolars, above the mylohyoid muscle insertion into the mandible. (Courtesy of Dr. Nathaniel Treister.)







Lichen Planusimage


image Incidence: 40-60% of individuals with LP have oropharyngeal involvement.


image Findings:


image Milky-white papules.


image Wickham striae: Reticulate (netlike) patterns of lacy-white hyperkeratosis [buccal mucosa (Fig. 33-6), lips, tongue, and gingivae].


image Hypertrophic LP—leukoplakia with Wickham striae usually on the buccal mucosa.


image Atrophic LP—shiny plaque often with Wickham striae in surrounding mucosa.


image Erosive/ulcerative LP—superficial erosions with overlying fibrin clots that are seen on the tongue and buccal mucosa; can be painful (Fig. 33-6).


image Bullous LP—intact blisters (rupture and result in erosive LP).


image Desquamative gingivitis—bright red gingiva (Fig. 33-7).






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Figure 33-6. Lichen planus: Wickham striae Poorly defined violaceous plaque with lacy, white pattern on the buccal mucosa.


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Figure 33-7. Lichen planus: desquamative gingivitis The gingival margins are erythematous, edematous, and retracted. The lesions were painful, making dental hygiene difficult, resulting in plaque formation on the teeth.







Acute Necrotizing Ulcerative Gingivitis image


image Precipitating factors: Poor oral hygiene, HIV/AIDS, immunosuppression, alcohol and tobacco use, nutritional deficiency.


image Findings (Fig. 33-8): Punched-out ulcers of the interdental papillae. Gingival hemorrhage, severe pain, foul odor/halitosis, fever, lymphadenopathy; alveolar bone destruction.


image Etiologic agents: Bacteroides fusiformis, Prevotella intermedia, Borrelia vincentii, Treponema.


image Management: Systemic antibiotics such as clindamycin, metronidazole, amoxicillin. Dental hygiene.


image Synonyms: Trench mouth, Vincent disease.






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Figure 33-8. Acute necrotizing ulcerative gingivitis (ANUG) Very painful gingivitis with necrosis on marginal gingiva, edema, purulence, and halitosis in a 35-year-old female with advanced HIV disease. ANUG resolved with oral clindamycin.







Gingival Hyperplasia image


image Findings: Hypertrophy of both the free and attached gingivae, particularly the interdental papillae (Fig. 33-9).


image Inflammatory enlargement: Most common cause of gingival enlargement. Caused by edema and infective cellular infiltration caused by prolonged exposure to bacterial plaque; fibrosis occurs if untreated.


image Drug-induced fibrous hyperplasia of gingivae: May cover the teeth and is associated with:


image Anticonvulsants: phenytoin, succinimides, valproic acid.


image Calcium channel blockers: nifedipine, verapamil.


image Cyclosporine.


image Systemic conditions/disorders:


image Pregnancy, puberty, vitamin C deficiency, glycogen storage disease.


image Chronic myelomonocytic leukemia (Fig. 33-9).





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Dec 17, 2016 | Posted by in Dermatology | Comments Off on 33 DISORDERS OF THE MOUTH

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