Chapter 19 Fig 19-4 (a,b) Condyloma accuminatum. (c) Condyloma accuminatum in situ hybridization for low risk HPV (types 6 and 11) Condylomata acuminata commonly have horn cysts and resemble seborrheic keratoses. The two are differentiated by areas of compact stratum corneum, round parakeratosis, coarse hypergranulosis, and vacuolated keratinocytes with large gray nuclei. In situ hybridization can identify the human papillomavirus (HPV) type. Bowenoid papulosis presents as discrete pink, brown, or gray lesions in the genitalia. They are typically sessile, rather than papillomatous or cauliflower-like. The histologic spectrum ranges from that of a condyloma with buckshot scatter of atypical cells to full-thickness atypia, indistinguishable from Bowen’s disease.
Viral infections, helminths, and arthropods
Viral infections
Warts
Condyloma acuminatum
Bowenoid papulosis
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