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Department of Dermatology, University of Pennsylvania, Penn Presbyterian Medical Center Medical Arts Building, Philadelphia, PA, USA
Abstract
Mastering a complex field like dermatology can initially be intimidating. I recommend trusting your own past methods of studying while focusing on learning the essential building blocks of our field. You must be able to describe clinical dermatologic conditions and key features in dermatopathology. Then you are ready to construct a differential diagnosis.
Keywords
Approach to studying dermatology1.1 General Advice on Studying
1.1.1 How to Study
Everyone has his or her own strategy for learning dermatology. Dermatology residents are often assigned to read textbooks, study unknown dermatopathology slides, and participate in teaching rounds, conferences, and grand rounds! These present a large amount of information, but of course, much of this knowledge is quickly forgotten.
If I have one piece of advice for studying dermatology, it is this: do not reinvent the wheel. Stick with whatever has worked for you in the past.
More and more, we are focusing our energy on “the boards.” Both the in-training examination and the American Board of Dermatology Certifying Examination test obscure facts and details that are important to know. You may be surrounded by residents whose impressive knowledge base about dermatologic disease is quite intimidating. Do not be afraid! It is great to learn trivia and excel at roundsmanship, but anybody can memorize facts if given the time. The important thing is to learn how to think like a master clinician and approach each patient in a logical, systematic manner. While certain facts must be memorized, try to organize and understand the concepts that support this knowledge. The best physicians know the facts (e.g., what the treatment for a disease is), but also have a broad understanding of the reasoning behind this choice (e.g., the targeted pathophysiology and the mechanism of action of the treatment). Conceptual learning provides the bedrock for memorizing and retaining facts.
1.1.2 Logic of This Book
When confronted with the need to classify species in 1857, Charles Darwin wrote, “It is good to have hair-splitters and lumpers. Those who make many species are the ‘splitters,’ and those who make few are the ‘lumpers.’” This line of thinking, the lumper-splitter dichotomy, is quite applicable to the categorization of dermatologic diseases.
A lumper believes there are many names for the same disease, perhaps because observers of that same disease are able to distinguish subtly different forms. It is simpler to learn a classification with fewer categories.
A splitter sees all the subtle differences and variations in disease processes and hopes to define optimal treatments by applying the scientific method to each separately categorized condition.
This book assigns merit to both the lumper and splitter worlds. There is value in lumping diseases into categories for the sake of easy learning and understanding, though admittedly sometimes this forces diseases into groups in which they may not cleanly fit.
On the other hand, splitting diseases by enumerating different names and distinctions permits more in depth learning about diseases in a broader category while defining distinctive features.
When I was a resident, I found that textbook readings, lectures, and other didactics blended together unpredictably, and often specific topics were taught in very different ways by each professor. There was also a large amount of important information that was not clearly presented in textbooks or manuals. In order to gain focus, I began to compile outlines and lists of everything I learned in an effort to unify various perspectives and points of view, and also to collect factoids and mnemonics so that I could study important material the same way every time. My notes reflect an organic mix of teachings during residency and as an attending dermatologist including information from lectures, textbooks, clinical articles, and personal experience. My goal is combine and organize this information in a systematic and logical way so that it is easier to learn. To simplify the presentation, I have not listed references. In the main outlines, I have focused on the important high yield and key conceptual points, yet still the information is comprehensive.
1.2 Describing Skin Conditions
Though it seems deceptively simple, learning to describe skin findings is a critically important skill. All physicians must learn to translate clinical observations into clear language to organize information and communicate effectively with colleagues.
A description should include the primary and secondary lesions, distribution, colors, configuration, nature of borders, and shape. If relevant, texture and patterns may provide diagnostic information.
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Remember: it is critically important to generate a complete differential diagnosis; this is far more important than getting the one right diagnosis. In theory, your description should allow a listener who has not seen the patient to develop a mental picture that would allow him or her to develop a comprehensive differential diagnosis.
The description should lead to the differential, not the other way around. Often the first impression of diagnosis prompts the physician to describe features that match this initial impression (e.g., when we describe likely psoriatic lesions with “silvery scale”). This is a trap that limits the differential diagnosis.
It is best to avoid descriptive terms that define themselves (e.g., verrucous, psoriasiform, acneiform, herpetiform). These terms also lead to closed-minded thinking. If you must use these terms (and we all do use them as a crutch), try to use them to supplement more descriptive terms.
1.
Skin type: I to VI
The Fitzpatrick skin phototype scale runs from I to VI, describing a patient’s complexion and sensitivity to sun exposure.
Type I. Very white, fair, red/blonde hair/blue eyes (Irish). Always burns, never tans.
Type II. White. Usually burns, rarely tans.
Type III. White/olive skin. Sometimes burns, gradually tans.
Type IV. Brown skin, rarely burns, tans easily (Mediterranean, Latino).
Type V. Dark brown skin, very rarely burns (Middle eastern, Indian)
Type VI. Black skin, never burns, always tans (African).
2.
Distribution/Location
Where are the skin lesions located? Generalized, bilateral/unilateral, sun exposed, intertriginous, extensor/flexural surfaces, acral (distal body such as hands and feet)?
Make sure you know the difference between distribution and configuration.
3.
Configuration
How lesions are arranged? Confluent vs. discrete, scattered, clustered/grouped, geometric/linear, dermatomal, serpiginous, Blaschkoid, nevoid
Certain shapes and configurations are almost always caused by external forces (e.g., geometric/linear) suggesting an “outside job,” such as contact dermatitis or Koebner phenomenon.
Blaschkoid = linear/whorled (like marble) along an embryologic line of Blaschko
Nevoid = A distinct configuration, well-demarcated, unilateral
4.
Primary lesions
Primary lesions of skin disease are extremely valuable features that are unmodified by external forces (see Primary Lesions section)
5.
Secondary lesions
Modification of primary lesion from evolution, trauma, or other external influence (see Secondary Lesions section)
If an examination reveals only secondary lesions, the findings may be entirely secondary to external influences such as scratching, “an outside job.” Tip: ask your patient, “Which came first, the itch or the rash?”
6.
Color
This can be subjective, but describe each skin condition the best you can.
Try to use specific colors with description of normal skin color as comparison rather than just “hyperpigmented” or “hypopigmented.”
“Depigmented” (no color/white) should only be used to describe a finding if the Wood’s lamp or biopsy have confirmed that pigment is completely lost. Wood’s lamp enhances epidermal pigment change, but not dermal.
Know the distinguishing features between these terms (especially erythema vs. purpura):
Erythematous = red and blanches (on palpation or diascopy) since from vasodilatation
Violaceous = purple (dermatologists may use “violaceous” rather than purple to avoid confusion with “purpuric”)
Purpuric = red/purple non-blanching caused by extravasation of blood
Dusky = dark purple/grey (suggests necrosis)
It can be difficult to distinguish between purpura and early necrosis.
7.
Borders
Regular vs. irregular, blurred vs. sharp/well-demarcated, scalloped, punched-out
8.
Shape
A.
Annular (round with central clearing)
B.
Round/nummular/discoid (no central clearing)
C.
Ovoid (oval-like e.g., pityriasis rosea)
D.
Serpiginous (snake-like)
E.
Targetoid: refers specifically to erythema multiforme lesions with three zones: dusky or blistered center, surrounded by white ring, and then erythema (as opposed to urticaria, which displays central clearing)
F.
Polycyclic (multiple overlapping annular)
G.
Arcuate (incomplete annular arc)
H.
Polymorphous (many shapes)
9.
Texture