Shoulder: Rotator Cuff

Anabolic Steroids Reduce Muscle Damage Caused by Rotator Cuff Tendon Release in an Experimental Study in Rabbits

Gerber C, Meyer DC, Nuss KM, et al (Univ of Zürich, Switzerland) J Bone Joint Surg Am 93:2189-2195, 2011^§

Abstract

Background

Muscles of the rotator cuff undergo retraction, atrophy, and fatty infiltration after a chronic tear, and a rabbit model has been used to investigate these changes. The purpose of this study was to test the hypothesis that the administration of anabolic steroids can diminish these muscular changes following experimental supraspinatus tendon release in the rabbit.

Methods

The supraspinatus tendon was released in twenty New Zealand White rabbits. Musculotendinous retraction was monitored over a period of six weeks. The seven animals in group I had no additional intervention, the six animals in group II had local and systemic administration of nandrolone decanoate, and the seven animals in group III had systemic administration of nandrolone decanoate during the six weeks. Two animals (group III) developed a postoperative infection and were excluded from the analysis. At the time that the animals were killed, in vivo muscle performance as well as imaging and histological muscle changes were investigated.

Only gold members can continue reading. Log In or Register to continue

Share this:

• Click to share on Twitter (Opens in new window)
• Click to share on Facebook (Opens in new window)

Related

Related posts:

of a Method of 4-Corner Arthrodesis Using Headless Compression Screws Hand: Bone and Ligament Fractures of the Distal Radius: The Effects of Delayed Debridement and Immediate Internal Fixation on Infection Rates and the Need for Secondary Procedures Head and Neck Fractures: Functional Results and Predictors of Outcome of Pain and Function in Patients With Symptomatic, Atraumatic Full-Thickness Rotator Cuff Tears: A Time-Zero Analysis of a Prospective Patient Cohort Enrolled in a Structured Physical Therapy Program in vivo engineered nerve conduit–fabrication and experimental study in rats

Stay updated, free articles. Join our Telegram channel

Join