Reward, Reinforcement, and Impulsivity in Obesity

 

Personality

Neuropsychological tests

Brain systems

SR/SP

Neuroticism

Conscient.

Cue-induced attention

Reinforce. value

Response inhibition

Impulsive choice

Interoception

Reward

Cognitive control

Children/Adolescents

↓ SR

↑ Urgency with ↑ BMI

NS

NS

↑ Food reinforcing value

↓ Motor Inhibition: (Stop Signal & GNG)

↑ Delay discounting

↑ Preference Reward/Risk choices (IGT)

↑ Correlation Gray matter SII and SR

↑ BOLD

SII, Insula, Frontal Oper. & ACC during Food Anticipation

↓ BOLD Insula during Impulsive Choice

↑ Gray matter Hippocamp.

↑ BOLD Midbrain during Impulsive Choice

↑ BOLD activation of dlPFC during Food Visual Cues

Adults

↓ SR

↑ SP

↑ Urgency

↑ Lack of perseverance

NS Reaction Times

↑ Eye-tracked Attention to Food

↑ BOLD signal during Money Anticipation

↑ Food reinforcing value

↓ Motor Inhibition (Stop Signal)

↓ Primed Words Inhibition

(Hayling Test)

↑ Delay discounting

NS Preference Reward/Risk choices (IGT)

↓ Reflection (Maze Tests)

↓ Gray matter Frontal Operculum

↓ Connectivity Insula

↓ Gray matter Dorsal Striatum & Cerebellum

↑ BOLD mPFC, Striatum & Hippocampus during Food (& Money) Anticipation

↓ Gray matter Dorsolateral Prefrontal Cortex

↓ BOLD Anterior Insula on Stop Signal





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Mar 27, 2016 | Posted by in General Surgery | Comments Off on Reward, Reinforcement, and Impulsivity in Obesity

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